Effect of Biomin®IMBO on the humoral immune response of broiler chickens

Abstract

This experiment was performed to study the effect of the synbiotic Biomin®IMBO on the humoral immunity of Ross 308 strain broilers. Birds (n=200) were randomly assigned to 5 treatments (4 replicates of 10 birds each). Treatments were as follows: (1) Control; (2) 0.75 × Biomin®IMBO manufacturer’s level (ML); (3); Biomin®IMBO at ML recommended (1 × Biomin®IMBO ML), (4) 1.25 × Biomin®IMBO ML; and (5) 1.5 × Biomin®IMBO ML. The birds received the synbiotic through the diet and were immunised with double doses of infectious bronchitis virus (IBV), Newcastle Disease virus (NDV) and Gumboro Disease (Infectious Bursal Disease virus, IBDV) vaccines and sheep red blood cells (SRBC) to evaluate humoral immunity by assessing antibody titres one week after the second immunisation, except for SRBC (one week after each immunisation). All levels of synbiotic given resulted in similar antibody titres against IBV, NDV and IBDV compared to the control group. However, birds receiving 1.0 × and 1.5 × Biomin®IMBO ML had higher titres against SRBC in both primary and secondary antibody responses. The data obtained from the experiment indicated that supplementing the feed with the synbiotic Biomin®IMBO increased the humoral immunity response of broilers against sheep red blood cells.