Mostrar el registro sencillo del ítem
dc.contributor.author
Ortega, Francisco Gabriel
dc.contributor.author
Fernández Baldo, Martín Alejandro
dc.contributor.author
Fernández, Jorge Gastón
dc.contributor.author
Serrano, Maria J.
dc.contributor.author
Sanz Ferramola, Maria Isabel
dc.contributor.author
Diaz Mochón, Juan J.
dc.contributor.author
Lorente, José Antonio
dc.contributor.author
Raba, Julio
dc.date.available
2016-05-23T19:09:23Z
dc.date.issued
2015-03
dc.identifier.citation
Ortega, Francisco Gabriel; Fernández Baldo, Martín Alejandro; Fernández, Jorge Gastón; Serrano, Maria J.; Sanz Ferramola, Maria Isabel; et al.; Study of antitumor activity in breast cell lines using silver nanoparticles produced by yeast; Dove Press; International Journal of Nanomedicine; 10; 1; 3-2015; 2021-2031
dc.identifier.issn
1176-9114
dc.identifier.uri
http://hdl.handle.net/11336/5780
dc.description.abstract
In the present article, we describe a study of antitumor activity in breast cell lines using silver nanoparticles (Ag NPs) synthesized by a microbiological method. These Ag NPs were tested for their antitumor activity against MCF7 and T47D cancer cells and MCF10-A normal breast cell line. We analyzed cell viability, apoptosis induction and endocytosis activity of those cell lines and we observed that the effects of the biosynthesized Ag NPs were directly related with the endocytosis activity. Moreover, Ag NPs had higher inhibition efficacy in tumor lines than in normal lines of breast, which is due to the higher endocytic activity of tumor cells comparing to normal cells. In this way, we are demonstrating that biosynthesized Ag NPs can be an alternative for the treatment of tumors.
dc.format
application/pdf
dc.language.iso
eng
dc.publisher
Dove Press
dc.rights
info:eu-repo/semantics/openAccess
dc.rights.uri
https://creativecommons.org/licenses/by-nc/2.5/ar/
dc.subject
Apoptosis
dc.subject
Breast Cancer
dc.subject
Silver Nanoparticles
dc.subject
Nanotechnology
dc.subject
Cancer
dc.subject
Microbiological Synthesis
dc.subject.classification
Nano-materiales
dc.subject.classification
Nanotecnología
dc.subject.classification
INGENIERÍAS Y TECNOLOGÍAS
dc.title
Study of antitumor activity in breast cell lines using silver nanoparticles produced by yeast
dc.type
info:eu-repo/semantics/article
dc.type
info:ar-repo/semantics/artículo
dc.type
info:eu-repo/semantics/publishedVersion
dc.date.updated
2016-05-16T20:18:07Z
dc.identifier.eissn
1178-2013
dc.journal.volume
10
dc.journal.number
1
dc.journal.pagination
2021-2031
dc.journal.pais
Nueva Zelanda
dc.journal.ciudad
Auckland
dc.description.fil
Fil: Ortega, Francisco Gabriel. Universidad de Granada. Centro de Genómica e Investigación Oncológica; España
dc.description.fil
Fil: Fernández Baldo, Martín Alejandro. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico San Luis. Instituto de Química de San Luis; Argentina
dc.description.fil
Fil: Fernández, Jorge Gastón. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico San Luis. Instituto de Química de San Luis; Argentina
dc.description.fil
Fil: Serrano, Maria J.. Universidad de Granada. Centro de Genómica e Investigación Oncológica; España
dc.description.fil
Fil: Sanz Ferramola, Maria Isabel. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico San Luis. Instituto de Química de San Luis; Argentina
dc.description.fil
Fil: Diaz Mochón, Juan J.. Universidad de Granada. Centro de Genómica e Investigación Oncológica; España
dc.description.fil
Fil: Lorente, José Antonio. Universidad de Granada. Centro de Genómica e Investigación Oncológica; España
dc.description.fil
Fil: Raba, Julio. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico San Luis. Instituto de Química de San Luis; Argentina
dc.journal.title
International Journal of Nanomedicine
dc.relation.alternativeid
info:eu-repo/semantics/altIdentifier/url/https://www.dovepress.com/study-of-antitumor-activity-in-breast-cell-lines-using-silver-nanopart-peer-reviewed-article-IJN
dc.relation.alternativeid
info:eu-repo/semantics/altIdentifier/url/http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4368032/
dc.relation.alternativeid
info:eu-repo/semantics/altIdentifier/pmid/PMC4368032
dc.relation.alternativeid
info:eu-repo/semantics/altIdentifier/doi/10.2147%2FIJN.S75835
dc.relation.alternativeid
info:eu-repo/semantics/altIdentifier/doi/http://dx.doi.org/10.2147%2FIJN.S75835
Archivos asociados