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dc.contributor.author
Hernández Vásquez, A.
dc.contributor.author
Molinari, L.
dc.contributor.author
Larrea, N.
dc.contributor.author
Ciapponi, Agustín
dc.date.available
2018-08-28T19:53:15Z
dc.date.issued
2017-12
dc.identifier.citation
Hernández Vásquez, A.; Molinari, L.; Larrea, N.; Ciapponi, Agustín; Psoriasis in Latin America and the Caribbean: a systematic review; Wiley Blackwell Publishing, Inc; Journal Of The European Academy Of Dermatology And Venereology; 31; 12; 12-2017; 1991-1998
dc.identifier.issn
0926-9959
dc.identifier.uri
http://hdl.handle.net/11336/57422
dc.description.abstract
Psoriasis is a chronic inflammatory disease that generally affects the skin, nails and joints. The burden of psoriatic disease in Latin America and the Caribbean (LAC) remains largely unknown. To estimate the burden of psoriasis in LAC. We conducted a systematic review following the MOOSE and PRISMA statements. We searched published studies in MEDLINE, EMBASE, LILACS and CENTRAL from 1st January 2000 to 5th August 2015. We included studies that reported incidence, prevalence, health resource use and health expenditures, treatment patterns, comparative effectiveness of different drugs, patients reported outcomes, adherence to treatment and patient preferences in LAC. Risk of bias was assessed evaluating selection of participants, control of cofounders, measurement of exposure and outcome and conflict of interest. Pairs of reviewers independently selected, extracted and assessed the bias risk of the studies. The systematic review was registered at PROSPERO (CRD42016038325). A total of 18 studies from 12 LAC countries were included. Most were observational studies, between which there was a large heterogeneity of outcomes. Population-based studies were not found and most data came from hospital registries. One study reported an incidence of psoriatic arthritis in 6.26 cases per 100 000 person-years. Another study found an incidence of psoriasis 1020 per 100 000 patient-year attending at a dermatology clinic. The prevalence reported in the Argentinean health service was 74 cases per 100 000. Further, psoriasis has been shown to have a substantial negative impact on quality of life. A number of studies also indicated that non-communicable disease burden increases with the presence and severity of psoriasis. With regard to treatment pattern, methotrexate was the dominant systemic therapy. In conclusion, there is an important lack of information from LAC concerning the burden of psoriasis. Further studies investigating the burden of psoriasis in representative LAC populations are needed.
dc.format
application/pdf
dc.language.iso
eng
dc.publisher
Wiley Blackwell Publishing, Inc
dc.rights
info:eu-repo/semantics/openAccess
dc.rights.uri
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
dc.subject
Psoriasis in Latin America
dc.subject.classification
Otras Ciencias de la Salud
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Ciencias de la Salud
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CIENCIAS MÉDICAS Y DE LA SALUD
dc.title
Psoriasis in Latin America and the Caribbean: a systematic review
dc.type
info:eu-repo/semantics/article
dc.type
info:ar-repo/semantics/artículo
dc.type
info:eu-repo/semantics/publishedVersion
dc.date.updated
2018-08-27T17:59:42Z
dc.journal.volume
31
dc.journal.number
12
dc.journal.pagination
1991-1998
dc.journal.pais
Reino Unido
dc.journal.ciudad
Londres
dc.description.fil
Fil: Hernández Vásquez, A.. Instituto de Efectividad Clínica y Sanitaria; Argentina. Universidad Privada del Norte; Perú
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Fil: Molinari, L.. Hospital Italiano; Argentina
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Fil: Larrea, N.. Instituto de Efectividad Clínica y Sanitaria; Argentina
dc.description.fil
Fil: Ciapponi, Agustín. Instituto de Efectividad Clínica y Sanitaria; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina
dc.journal.title
Journal Of The European Academy Of Dermatology And Venereology
dc.relation.alternativeid
info:eu-repo/semantics/altIdentifier/doi/http://dx.doi.org/10.1111/jdv.14393
dc.relation.alternativeid
info:eu-repo/semantics/altIdentifier/url/https://onlinelibrary.wiley.com/doi/abs/10.1111/jdv.14393
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