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dc.contributor.author
Masuelli, Martin Alberto
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dc.date.available
2016-05-16T20:37:58Z
dc.date.issued
2013-05
dc.identifier.citation
Masuelli, Martin Alberto; Study of Bovine Serum Albumin Solubility in Aqueous Solutions by Intrinsic Viscosity Measurements; Hindawi Publishing Corporation; Advances in Physical Chemistry; 2013; 5-2013; 360239-360239
dc.identifier.issn
1687-7993
dc.identifier.uri
http://hdl.handle.net/11336/5698
dc.description.abstract
The behavior of bovine serum albumin (BSA) in water is scarcely studied, and the thermodynamic properties arising from the experimental measurements have not been reported. Intrinsic viscosity measurements are very useful in assessing the interaction between the solute and solvent. This work discussed in a simple determination of the enthalpy of BSA in aqueous solution when the concentration ranges from 0.2 to 36.71% wt. and the temperature from 35 to 40ºC. The relationship between the concentration and intrinsic viscosity is determined according to the method of Huggins. The temperature increase reduces the ratio between inherent viscosity and concentration (/). This is reflected in the Van't Hoff curve. Furthermore, this work proposes hydrodynamic cohesion value as an indicator of the degree of affinity of protein with water and thermodynamic implications in conformational changes.
dc.format
application/pdf
dc.language.iso
eng
dc.publisher
Hindawi Publishing Corporation
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dc.rights
info:eu-repo/semantics/openAccess
dc.rights.uri
https://creativecommons.org/licenses/by/2.5/ar/
dc.subject
Bovine Serum Albumin
dc.subject
Solubility
dc.subject
Aqueous Solutions
dc.subject
Intrinsic Viscosity
dc.subject.classification
Bioquímica y Biología Molecular
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dc.subject.classification
Ciencias Biológicas
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dc.subject.classification
CIENCIAS NATURALES Y EXACTAS
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dc.title
Study of Bovine Serum Albumin Solubility in Aqueous Solutions by Intrinsic Viscosity Measurements
dc.type
info:eu-repo/semantics/article
dc.type
info:ar-repo/semantics/artículo
dc.type
info:eu-repo/semantics/publishedVersion
dc.date.updated
2016-05-13T13:44:24Z
dc.journal.volume
2013
dc.journal.pagination
360239-360239
dc.journal.pais
Estados Unidos
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dc.journal.ciudad
New York
dc.description.fil
Fil: Masuelli, Martin Alberto. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico San Luis. Instituto de Física Aplicada; Argentina. Universidad Nacional de San Luis. Departamento de Quimica; Argentina
dc.journal.title
Advances in Physical Chemistry
dc.relation.alternativeid
info:eu-repo/semantics/altIdentifier/doi/10.1155/2013/360239
dc.relation.alternativeid
info:eu-repo/semantics/altIdentifier/doi/http://dx.doi.org/10.1155/2013/360239
dc.relation.alternativeid
info:eu-repo/semantics/altIdentifier/url/http://www.hindawi.com/journals/apc/2013/360239/
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