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dc.contributor.author
Ocaña, Virginia Soledad
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dc.contributor.author
Silva de Ruiz, Clara
dc.contributor.author
Nader, Maria Elena Fatima
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dc.date.available
2018-08-21T14:54:33Z
dc.date.issued
2006-12
dc.identifier.citation
Ocaña, Virginia Soledad; Silva de Ruiz, Clara; Nader, Maria Elena Fatima; Antibiotic susceptibility of potentially probiotic vaginal lactobacilli; Hindawi Publishing Corporation; Infectious Diseases In Obstetrics And Gynecology; 2006; 18182; 12-2006; 1-6
dc.identifier.issn
1064-7449
dc.identifier.uri
http://hdl.handle.net/11336/56316
dc.description.abstract
Objective. To study the antimicrobial susceptibility of six vaginal probiotic lactobacilli. Methods. The disc diffusion method in Müeller Hinton, LAPTg and MRS agars by the NCCLS (National Committee for Clinical Laboratory Standards) procedure was performed. Due to the absence of a Lactobacillus reference strains, the results were compared to those of Staphylococcus aureus ATCC29213. Minimal Inhibitory Concentration (MIC) with 21 different antibiotics in LAPTg agar and broth was also determined. Results. LAPTg and MRS agars are suitable media to study antimicrobial susceptibility of lactobacilli. However, the NCCLS procedure needs to be standardized for this genus. The MICs have shown that all Lactobacillus strains grew at concentrations above 10 μg/mL of chloramphenicol, aztreonam, norfloxacin, ciprofloxacin, ceftazidime, ceftriaxone, streptomycin and kanamycin. Four lactobacilli were sensitive to 1 μg/mL vancomycin and all of them were resistant to 1000 μg/mL of metronidazole. Sensitivity to other antibiotics depended on each particular strain. Conclusions. The NCCLS method needs to be standardized in an appropriate medium to determine the antimicrobial susceptibility of Lactobacillus. Vaginal probiotic lactobacilli do not display uniform susceptibility to antibiotics. Resistance to high concentrations of metronidazole suggests that lactobacilli could be simultaneously used with a bacterial vaginosis treatment to restore the vaginal normal flora. Copyright
dc.format
application/pdf
dc.language.iso
eng
dc.publisher
Hindawi Publishing Corporation
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dc.rights
info:eu-repo/semantics/openAccess
dc.rights.uri
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
dc.subject
Vaginal Lactobacilli
dc.subject
Antibiotic
dc.subject
Susceptibility
dc.subject.classification
Otras Ciencias Biológicas
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dc.subject.classification
Ciencias Biológicas
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dc.subject.classification
CIENCIAS NATURALES Y EXACTAS
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dc.title
Antibiotic susceptibility of potentially probiotic vaginal lactobacilli
dc.type
info:eu-repo/semantics/article
dc.type
info:ar-repo/semantics/artículo
dc.type
info:eu-repo/semantics/publishedVersion
dc.date.updated
2018-07-23T18:10:58Z
dc.identifier.eissn
1098-0997
dc.journal.volume
2006
dc.journal.number
18182
dc.journal.pagination
1-6
dc.journal.pais
Egipto
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dc.journal.ciudad
Cairo
dc.description.fil
Fil: Ocaña, Virginia Soledad. Nuevo Hospital El Milagro; Argentina
dc.description.fil
Fil: Silva de Ruiz, Clara. Universidad Nacional de Tucumán. Facultad de Bioquímica, Química y Farmacia; Argentina
dc.description.fil
Fil: Nader, Maria Elena Fatima. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Tucumán. Centro de Referencia para Lactobacilos; Argentina
dc.journal.title
Infectious Diseases In Obstetrics And Gynecology
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dc.relation.alternativeid
info:eu-repo/semantics/altIdentifier/doi/http://dx.doi.org/10.1155/IDOG/2006/18182
dc.relation.alternativeid
info:eu-repo/semantics/altIdentifier/url/https://www.hindawi.com/journals/idog/2006/018182/abs/
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