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dc.contributor.author
Sanz-García, Ancor
dc.contributor.author
Vega Zelaya, Lorena
dc.contributor.author
Pastor, Jesús
dc.contributor.author
Torres, Cristina V.
dc.contributor.author
Sola, Rafael G.
dc.contributor.author
Ortega, Guillermo José
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dc.date.available
2018-08-16T15:31:41Z
dc.date.issued
2016-12
dc.identifier.citation
Sanz-García, Ancor; Vega Zelaya, Lorena; Pastor, Jesús; Torres, Cristina V.; Sola, Rafael G.; et al.; Network analysis of foramen ovale electrode recordings in drug-resistant temporal lobe epilepsy patients; Journal of Visualized Experiments; Journal of Visualized Experiments; 2016; 118; 12-2016; 1-10
dc.identifier.issn
1940-087X
dc.identifier.uri
http://hdl.handle.net/11336/55902
dc.description.abstract
Approximately 30% of epilepsy patients are refractory to antiepileptic drugs. In these cases, surgery is the only alternative to eliminate/control seizures. However, a significant minority of patients continues to exhibit post-operative seizures, even in those cases in which the suspected source of seizures has been correctly localized and resected. The protocol presented here combines a clinical procedure routinely employed during the pre-operative evaluation of temporal lobe epilepsy (TLE) patients with a novel technique for network analysis. The method allows for the evaluation of the temporal evolution of mesial network parameters. The bilateral insertion of foramen ovale electrodes (FOE) into the ambient cistern simultaneously records electrocortical activity at several mesial areas in the temporal lobe. Furthermore, network methodology applied to the recorded time series tracks the temporal evolution of the mesial networks both interictally and during the seizures. In this way, the presented protocol offers a unique way to visualize and quantify measures that considers the relationships between several mesial areas instead of a single area.
dc.format
application/pdf
dc.language.iso
eng
dc.publisher
Journal of Visualized Experiments
dc.rights
info:eu-repo/semantics/openAccess
dc.rights.uri
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
dc.subject
Foramen Ovale Electrodes
dc.subject
Issue 118
dc.subject
Limbic Networks
dc.subject
Medicine
dc.subject
Network Theory
dc.subject
Synchronization
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Temporal Lobe Epilepsy
dc.subject.classification
Medicina Critica y de Emergencia
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dc.subject.classification
Medicina Clínica
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dc.subject.classification
CIENCIAS MÉDICAS Y DE LA SALUD
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dc.title
Network analysis of foramen ovale electrode recordings in drug-resistant temporal lobe epilepsy patients
dc.type
info:eu-repo/semantics/article
dc.type
info:ar-repo/semantics/artículo
dc.type
info:eu-repo/semantics/publishedVersion
dc.date.updated
2018-08-15T14:57:25Z
dc.journal.volume
2016
dc.journal.number
118
dc.journal.pagination
1-10
dc.journal.pais
Estados Unidos
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dc.journal.ciudad
Cambridge
dc.description.fil
Fil: Sanz-García, Ancor. Hospital de la Princesa; España
dc.description.fil
Fil: Vega Zelaya, Lorena. Hospital de la Princesa; España
dc.description.fil
Fil: Pastor, Jesús. Hospital de la Princesa; España
dc.description.fil
Fil: Torres, Cristina V.. Hospital de la Princesa; España
dc.description.fil
Fil: Sola, Rafael G.. Hospital de la Princesa; España
dc.description.fil
Fil: Ortega, Guillermo José. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina. Hospital de la Princesa; España
dc.journal.title
Journal of Visualized Experiments
dc.relation.alternativeid
info:eu-repo/semantics/altIdentifier/doi/https://dx.doi.org/10.3791/54746
dc.relation.alternativeid
info:eu-repo/semantics/altIdentifier/url/https://www.jove.com/video/54746/network-analysis-foramen-ovale-electrode-recordings-drug-resistant
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