Artículo

Progesterone receptor assembly of a transcriptional complex along with activator protein 1, signal transducer and activator of transcription 3 and ErbB-2 governs breast cancer growth and predicts response to endocrine therapy

Díaz Flaqué, María CelesteIcon ; Galigniana, Natalia Maricel; Beguelin, Wendy; Vicario, Rocio; Proietti Anastasi, Cecilia JazmínIcon ; Cordo Russo, Rosalia InesIcon ; Rivas, Martin AlfredoIcon ; Tkach, MercedesIcon ; Guzmán, Pablo; Roa, Juan C.; Maronna, Esteban; Pineda, Viviana; Muñoz, Sergio; Mercogliano, María Florencia; Charreau, Eduardo HernanIcon ; Yankilevich, PatricioIcon ; Schillaci, RoxanaIcon ; Elizalde, Patricia VirginiaIcon
Fecha de publicación: 17/12/2013
Editorial: Biomed Central
Revista: Breast Cancer Research
ISSN: 1465-5411
e-ISSN: 1465-542X
Idioma: Inglés
Tipo de recurso: Artículo publicado
Clasificación temática:

Resumen

The role of the progesterone receptor (PR) in breast cancer remains a major clinical challenge. Although PR induces mammary tumor growth, its presence in breast tumors is a marker of good prognosis. We investigated coordinated PR rapid and nonclassical transcriptional effects governing breast cancer growth and endocrine therapy resistance.
Palabras clave: Pr , Breast Cancer , Endocrine Response , Tamoxifen Resistance , Ap-1 , Crosstalk
 
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info:eu-repo/semantics/openAccess Excepto donde se diga explícitamente, este item se publica bajo la siguiente descripción: Creative Commons Attribution 2.5 Unported (CC BY 2.5)
Identificadores
URI: http://hdl.handle.net/11336/5536
DOI: http://dx.doi.org/ 10.1186/bcr3587
DOI: http://dx.doi.org/10.1186/bcr3587
URL: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3978912/
URL: http://breast-cancer-research.biomedcentral.com/articles/10.1186/bcr3587
Colecciones
Articulos(IBIOBA - MPSP)
Articulos de INST. D/INV.EN BIOMED.DE BS AS-CONICET-INST. PARTNER SOCIEDAD MAX PLANCK
Articulos(IBYME)
Articulos de INST.DE BIOLOGIA Y MEDICINA EXPERIMENTAL (I)
Citación
Díaz Flaqué, María Celeste; Galigniana, Natalia Maricel; Beguelin, Wendy; Vicario, Rocio; Proietti Anastasi, Cecilia Jazmín; et al.; Progesterone receptor assembly of a transcriptional complex along with activator protein 1, signal transducer and activator of transcription 3 and ErbB-2 governs breast cancer growth and predicts response to endocrine therapy; Biomed Central; Breast Cancer Research; 15; 6; 17-12-2013; R118-118
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