Artículo
Fasciola hepatica products induce apoptosis of peritoneal macrophages
Fecha de publicación:
08/2012
Editorial:
Elsevier Science
Revista:
Veterinary Immunology And Immunopathology
ISSN:
0165-2427
Idioma:
Inglés
Tipo de recurso:
Artículo publicado
Clasificación temática:
Resumen
Immunomodulatory properties have been described for Fasciola hepatica excretory-secretory products (FhESP), with their interaction with the innate immune cells being crucial during the early stages of infection. Previously, we demonstrated that FhESP induce eosinophil apoptosis. In this work, the ability of FhESP to induce apoptosis of peritoneal macrophages was evaluated.These parasite products were observed to induce apoptosis in peritoneal macrophages stimulated in vitro with FhESP, as well as in cells recovered from infected mice. The ability of FhESP to modify the viability of macrophages by apoptosis induction may constitute a crucial event for extending its survival in the host. © 2012 Elsevier B.V.
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Licencia
Identificadores
Colecciones
Articulos(CCT - CORDOBA)
Articulos de CTRO.CIENTIFICO TECNOL.CONICET - CORDOBA
Articulos de CTRO.CIENTIFICO TECNOL.CONICET - CORDOBA
Articulos(CIBICI)
Articulos de CENTRO DE INV.EN BIOQUI.CLINICA E INMUNOLOGIA
Articulos de CENTRO DE INV.EN BIOQUI.CLINICA E INMUNOLOGIA
Citación
Guasconi, Lorena; Serradell, Marianela del Carmen.; Masih, Diana Teresa; Fasciola hepatica products induce apoptosis of peritoneal macrophages; Elsevier Science; Veterinary Immunology And Immunopathology; 148; 3-4; 8-2012; 359-363
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