Artículo
Protein adsorption onto nanomaterials for the development of biosensors and analytical devices: A review
Fecha de publicación:
04/05/2015
Editorial:
Elsevier Science
Revista:
Analytica Chimica Acta
ISSN:
0003-2670
Idioma:
Inglés
Tipo de recurso:
Artículo publicado
Clasificación temática:
Resumen
An important consideration for the development of biosensors is the adsorption of the biorecognition element to the surface of a substrate. As the first step in the immobilization process, adsorption affects most immobilization routes and much attention is given into the research of this process to maximize the overall activity of the biosensor. The use of nanomaterials, specifically nanoparticles and nanostructured films, offers advantageous properties that can be fine-tuned to maximize interactions with specific proteins to maximize activity, minimize structural changes, and enhance the catalytic step. In the biosensor field, protein-nanomaterial interactions are an emerging trend that span across many disciplines. This review addresses recent publications about the proteins most frequently used, their most relevant characteristics, and the conditions required to adsorb them to nanomaterials. When relevant and available, subsequent analytical figures of merits are discussed for selected biosensors. The general trend amongst the research papers allows concluding that the use of nanomaterials has already provided significant improvements in the analytical performance of many biosensors and that this research field will continue to grow.
Palabras clave:
Adsorption
,
Proteins
,
Nanomaterials
,
Biosensors
,
Oxidase
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Identificadores
Colecciones
Articulos(INFIQC)
Articulos de INST.DE INVESTIGACIONES EN FISICO- QUIMICA DE CORDOBA
Articulos de INST.DE INVESTIGACIONES EN FISICO- QUIMICA DE CORDOBA
Citación
Bhakta, Samir A.; Evans, Elizabeth; Benavidez, Tomás Enrique; Garcia, Carlos D; Protein adsorption onto nanomaterials for the development of biosensors and analytical devices: A review; Elsevier Science; Analytica Chimica Acta; 872; 4-5-2015; 7-25
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