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dc.contributor.author
Fernández van Raap, Marcela Beatriz
dc.contributor.author
Coral, Diego Fernando
dc.contributor.author
Yu, S.
dc.contributor.author
Muñoz Medina, Guillermo Arturo
dc.contributor.author
Sánchez, Francisco Homero
dc.contributor.author
Roig, A.
dc.date.available
2018-08-07T14:58:51Z
dc.date.issued
2017-01
dc.identifier.citation
Fernández van Raap, Marcela Beatriz; Coral, Diego Fernando; Yu, S.; Muñoz Medina, Guillermo Arturo; Sánchez, Francisco Homero; et al.; Anticipating hyperthermic efficiency of magnetic colloids using a semi-empirical model: A tool to help medical decisions; Royal Society of Chemistry; Physical Chemistry Chemical Physics; 19; 10; 1-2017; 7176-7187
dc.identifier.issn
1463-9076
dc.identifier.uri
http://hdl.handle.net/11336/54412
dc.description.abstract
Magnetic hyperthermia, a modality that uses radio frequency heating assisted with single-domain magnetic nanoparticles, is becoming established as a powerful oncological therapy. Much improvement in nanomaterials development, to enhance their heating efficiency by tuning the magnetic colloidal properties, has been achieved. However, methodological standardization to accurately and univocally determine the colloidal properties required to numerically reproduce a specific heating efficiency using analytical expressions still holds. Thus, anticipating the hyperthermic performances of magnetic colloids entails high complexity due to polydispersity, aggregation and dipolar interactions always present in real materials to a greater or lesser degree. Here, by numerically simulating the experimental results and using real biomedical aqueous colloids, we analyse and compare several approaches to reproduce experimental specific absorption rate values. Then, we show that the relaxation time, determined using a representative mean activation energy consistently derived from four independent experiments accurately reproduces experimental heating efficiencies. Moreover, the so-derived relaxation time can be used to extrapolate the heating performance of the magnetic nanoparticles to the other field conditions within the framework of the linear response theory. We thus present a practical tool that may truly aid the design of medical decisions.
dc.format
application/pdf
dc.language.iso
eng
dc.publisher
Royal Society of Chemistry
dc.rights
info:eu-repo/semantics/openAccess
dc.rights.uri
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
dc.subject
Magnetic Hyperthermia
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Magnetic Nanoparticles
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Medical Support
dc.subject.classification
Nano-materiales
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Nanotecnología
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INGENIERÍAS Y TECNOLOGÍAS
dc.title
Anticipating hyperthermic efficiency of magnetic colloids using a semi-empirical model: A tool to help medical decisions
dc.type
info:eu-repo/semantics/article
dc.type
info:ar-repo/semantics/artículo
dc.type
info:eu-repo/semantics/publishedVersion
dc.date.updated
2018-06-25T16:15:29Z
dc.journal.volume
19
dc.journal.number
10
dc.journal.pagination
7176-7187
dc.journal.pais
Reino Unido
dc.journal.ciudad
Cambridge
dc.description.fil
Fil: Fernández van Raap, Marcela Beatriz. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - La Plata. Instituto de Física La Plata. Universidad Nacional de La Plata. Facultad de Ciencias Exactas. Instituto de Física La Plata; Argentina
dc.description.fil
Fil: Coral, Diego Fernando. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - La Plata. Instituto de Física La Plata. Universidad Nacional de La Plata. Facultad de Ciencias Exactas. Instituto de Física La Plata; Argentina
dc.description.fil
Fil: Yu, S.. Consejo Superior de Investigaciones Científicas; España
dc.description.fil
Fil: Muñoz Medina, Guillermo Arturo. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - La Plata. Instituto de Física La Plata. Universidad Nacional de La Plata. Facultad de Ciencias Exactas. Instituto de Física La Plata; Argentina
dc.description.fil
Fil: Sánchez, Francisco Homero. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - La Plata. Instituto de Física La Plata. Universidad Nacional de La Plata. Facultad de Ciencias Exactas. Instituto de Física La Plata; Argentina
dc.description.fil
Fil: Roig, A.. Consejo Superior de Investigaciones Científicas; España
dc.journal.title
Physical Chemistry Chemical Physics
dc.relation.alternativeid
info:eu-repo/semantics/altIdentifier/doi/https://dx.doi.org/10.1039/C6CP08059F
dc.relation.alternativeid
info:eu-repo/semantics/altIdentifier/url/http://pubs.rsc.org/en/Content/ArticleLanding/2017/CP/C6CP08059F
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