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dc.contributor.author
Haag, Griselda Octavia
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dc.contributor.author
Marin, Gustavo Horacio
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dc.contributor.author
Errecalde, Jorge Oscar
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dc.date.available
2018-08-03T17:52:59Z
dc.date.issued
2016-01
dc.identifier.citation
Haag, Griselda Octavia; Marin, Gustavo Horacio; Errecalde, Jorge Oscar; Quantification of residual enrofloxacin and ciprofloxacin in feathers of broiler chickens by high-performance liquid chromatography-fluorescence after oral administration of the drugs; Medknow Publications; Journal of Advanced Pharmaceutical Technology and Research; 7; 1; 1-2016; 2-5
dc.identifier.issn
2231-4040
dc.identifier.uri
http://hdl.handle.net/11336/54095
dc.description.abstract
Enrofloxacin (ENR) and ciprofloxacin (CIP) are drugs used in poultry feeding. In general, feathers that are incorporated in the food chain as a protein source for animal feed, have residues of these drugs. In order to study the pharmacokinetic of ENR/CIP residues in feathers of broiler chickens, to calculate the waiting times for these drugs, before human consumption, we developed the present research. Feathers of broiler chickens were enriched with ENR/CIP. After adding acetone, the mix was agitated and centrifuged and supernatant evaporated under nitrogen. The dry residue was suspended in a tetrahydrofuran solution and the supernatant was injected into the chromatographic system for analysis. Animals showed high levels of ENR/CIP in their feathers after administration of 10 mg/kg enrofloxacin dissolved in drinking water for 5 days. Both compounds were detected in feathers during 9 days. The analytical method developed in this paper to determine ENR and CIP in feathers of broiler chicken showed good linearity, selectivity, accuracy and precision in the analysis conditions. This technique could have important applications in the studies on residues of ENR/CIP in feathers, since the effect of this component in animal diets has not been considered yet.
dc.format
application/pdf
dc.language.iso
eng
dc.publisher
Medknow Publications
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dc.rights
info:eu-repo/semantics/openAccess
dc.rights.uri
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
dc.subject
Enrofloxacin
dc.subject
Quantification
dc.subject
Quinolones
dc.subject.classification
Inmunología
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dc.subject.classification
Medicina Básica
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dc.subject.classification
CIENCIAS MÉDICAS Y DE LA SALUD
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dc.title
Quantification of residual enrofloxacin and ciprofloxacin in feathers of broiler chickens by high-performance liquid chromatography-fluorescence after oral administration of the drugs
dc.type
info:eu-repo/semantics/article
dc.type
info:ar-repo/semantics/artículo
dc.type
info:eu-repo/semantics/publishedVersion
dc.date.updated
2018-08-03T14:16:19Z
dc.identifier.eissn
0976-2094
dc.journal.volume
7
dc.journal.number
1
dc.journal.pagination
2-5
dc.journal.pais
Estados Unidos
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dc.journal.ciudad
Filadelfia
dc.description.fil
Fil: Haag, Griselda Octavia. Universidad Nacional de La Plata; Argentina
dc.description.fil
Fil: Marin, Gustavo Horacio. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - La Plata; Argentina. Universidad Nacional de La Plata; Argentina
dc.description.fil
Fil: Errecalde, Jorge Oscar. Universidad Nacional de La Plata; Argentina
dc.journal.title
Journal of Advanced Pharmaceutical Technology and Research
dc.relation.alternativeid
info:eu-repo/semantics/altIdentifier/url/https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4759981/
dc.relation.alternativeid
info:eu-repo/semantics/altIdentifier/doi/http://dx.doi.org/10.4103/2231-4040.173265
dc.relation.alternativeid
info:eu-repo/semantics/altIdentifier/url/http://www.japtr.org/article.asp?issn=2231-4040;year=2016;volume=7;issue=1;spage=2;epage=5;aulast=Haag
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