Artículo
Analysis of 15 autosomal STR loci from Mar del Plata and Bahia Blanca (Central Region of Argentina)
Parolin, María Laura
; Carreras Torres, Robert; Sambuco, Lorena Andrea
; Jaureguiberry, Stella Maris; Iudica, Celia Estela
Fecha de publicación:
10/2013
Editorial:
Springer
Revista:
International Journal of Legal Medicine
ISSN:
0937-9827
Idioma:
Inglés
Tipo de recurso:
Artículo publicado
Clasificación temática:
Resumen
Allele frequencies for the 15 short tandem repeats (STRs) loci included in the AmpFlSTR® Identifiler kit were estimated in a sample of unrelated individuals from Mar del Plata (MDQ, N= 180) and Bahia Blanca (BB, N= 85) (Buenos Aires, Argentina). Biological samples were obtained from voluntary donors and forensic cases. Both populations were in Hardy-Weinberg equilibrium after Bonferroni correction, except for locus vWA in MDQ and D2S1338 in BB. FGA was the most informative locus and the least discriminating locus was TPOX in both samples. The combined Power of Discrimination (PDc) and the combined Probability of Exclusion (PEc) were similar in MDQ and BB samples (0.999999998< PDc <0.999999999 and 0.999999979 < PEc < 0.999999989). The multidimentional scaling (MDS) plot from Rst genetic distance matrix and the interethnic admixture estimation supported a higher European contribution in populations of Central Region, compared with populations from other regions of Argentina with higher Amerindian composition. These results enlarge the Argentine databases of autosomal STR loci, revealed as an excellent tool for human identification tests and population genetic analysis.
Palabras clave:
Autosomal Strs
,
Admixed Population
,
Population Genetic Structure
Archivos asociados
Licencia
Identificadores
Colecciones
Articulos(CCT-CENPAT)
Articulos de CTRO.CIENTIFICO TECNOL.CONICET - CENPAT
Articulos de CTRO.CIENTIFICO TECNOL.CONICET - CENPAT
Citación
Parolin, María Laura; Carreras Torres, Robert; Sambuco, Lorena Andrea; Jaureguiberry, Stella Maris; Iudica, Celia Estela; Analysis of 15 autosomal STR loci from Mar del Plata and Bahia Blanca (Central Region of Argentina); Springer; International Journal of Legal Medicine; 128; 3; 10-2013; 457-459
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