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dc.contributor.author
Roberts, Mark L.
dc.contributor.author
Buchanan, Katherine L.
dc.contributor.author
Evans, Matthew R.
dc.contributor.author
Marin, Raul Hector
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dc.contributor.author
Satterlee,Daniel G.
dc.date.available
2018-07-26T20:02:27Z
dc.date.issued
2009-10
dc.identifier.citation
Roberts, Mark L.; Buchanan, Katherine L.; Evans, Matthew R.; Marin, Raul Hector; Satterlee,Daniel G.; The effects of testosterone on immune function in quail selected for divergent plasma corticosterone response; Company of Biologists; Journal of Experimental Biology; 212; 19; 10-2009; 3125-3131
dc.identifier.issn
0022-0949
dc.identifier.uri
http://hdl.handle.net/11336/53232
dc.description.abstract
The immunocompetence handicap hypothesis (ICHH) suggests that the male sex hormone testosterone has a dual effect; it controls the development and expression of male sexually selected signals, and it suppresses the immune system. Therefore only high quality males are able to fully express secondary sexual traits because only they can tolerate the immunosuppressive qualities of testosterone. A modified version of the ICHH suggests that testosterone causes immunosuppression indirectly by increasing the stress hormone corticosterone (CORT). Lines of Japanese quail (Coturnix japónica) selected for divergent responses in levels of plasma CORT were used to test these hypotheses. Within each CORT response line (as well as in a control stock) we manipulated levels of testosterone in castrated quail by treatment with zero (sham), low or high testosterone implants, before testing the birds' humoral immunity and phytohaemagglutinin (PHA)-induced immune response, as well as body condition. The PHA-induced response was not significantly affected by CORT selected line, testosterone treatment or their interaction. There was, however, a significant effect of CORT line on humoral immunity in that the control birds exhibited the greatest antibody production, but there was no significant effect of testosterone manipulation on humoral immunity. The males in the sham implant treatment group had significantly greater mass than the males in the high testosterone group, suggesting a negative effect of high testosterone on general body condition. We discuss these results in the context of current hypotheses in the field of sexual selection.
dc.format
application/pdf
dc.language.iso
eng
dc.publisher
Company of Biologists
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dc.rights
info:eu-repo/semantics/openAccess
dc.rights.uri
https://creativecommons.org/licenses/by-nc/2.5/ar/
dc.subject
Corticosterone
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Immunity
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Japanese Quail
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Pha
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Srbc
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Stress
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Testosterone
dc.subject.classification
Biología
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dc.subject.classification
Ciencias Biológicas
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dc.subject.classification
CIENCIAS NATURALES Y EXACTAS
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dc.title
The effects of testosterone on immune function in quail selected for divergent plasma corticosterone response
dc.type
info:eu-repo/semantics/article
dc.type
info:ar-repo/semantics/artículo
dc.type
info:eu-repo/semantics/publishedVersion
dc.date.updated
2018-07-23T17:29:23Z
dc.identifier.eissn
1477-9145
dc.journal.volume
212
dc.journal.number
19
dc.journal.pagination
3125-3131
dc.journal.pais
Reino Unido
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dc.journal.ciudad
Cambridge
dc.description.fil
Fil: Roberts, Mark L.. Imperial College London; Reino Unido
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Fil: Buchanan, Katherine L.. Deakin University; Australia
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Fil: Evans, Matthew R.. University of Exeter; Reino Unido
dc.description.fil
Fil: Marin, Raul Hector. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Córdoba. Instituto de Investigaciones Biológicas y Tecnológicas. Universidad Nacional de Córdoba. Facultad de Ciencias Exactas, Físicas y Naturales. Instituto de Investigaciones Biológicas y Tecnológicas; Argentina
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Fil: Satterlee,Daniel G.. State University of Louisiana; Estados Unidos
dc.journal.title
Journal of Experimental Biology
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dc.relation.alternativeid
info:eu-repo/semantics/altIdentifier/url/http://jeb.biologists.org/content/212/19/3125
dc.relation.alternativeid
info:eu-repo/semantics/altIdentifier/doi/http://dx.doi.org/10.1242/jeb.030726
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