Cross-Metathesis on Immobilized Substrates – Application to the Generation of Synthetically and Biologically Relevant Structures

Abstract

Olefin metathesis constitutes a seemingly endless area of research that has had an enormous impact on several branches of chemistry, both in industry and in academia. Once the potential of this reaction as a carbon–carbon bond-forming tool was widely recognized, its adaptation to solid-phase chemistry naturally followed. This review documents the applications and possibilities that polymer-bound alkenes have provided in the challenging cross-version of olefin metathesis, through efforts that are far from exhausted.