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dc.contributor.author
Huang, Peng  
dc.contributor.author
Li, Chunshun  
dc.contributor.author
Sarotti, Ariel Marcelo  
dc.contributor.author
Turkson, James  
dc.contributor.author
Cao, Shugeng  
dc.date.available
2018-07-26T18:46:19Z  
dc.date.issued
2017-02  
dc.identifier.citation
Huang, Peng; Li, Chunshun; Sarotti, Ariel Marcelo; Turkson, James; Cao, Shugeng; Sphaerialactonam, a γ-lactam–isochromanone from the Hawaiian endophytic fungus Paraphaeosphaeria sp. FT462; Pergamon-Elsevier Science Ltd; Tetrahedron Letters; 58; 13; 2-2017; 1330-1333  
dc.identifier.issn
0040-4039  
dc.identifier.uri
http://hdl.handle.net/11336/53191  
dc.description.abstract
Reinvestigation of the endophytic fungus Paraphaeosphaeria sp. FT462 from the Hawaiian plant Lycopodiella cernua (L.) Pic. Serm led to the isolation and identification of a unique γ-lactam-isochromanone (1). The structure of 1 was determined by NMR, MS spectroscopic analysis, and quantum chemical calculations of NMR. The compound was tested inactive against A2780 and A2780cisR.  
dc.format
application/pdf  
dc.language.iso
eng  
dc.publisher
Pergamon-Elsevier Science Ltd  
dc.rights
info:eu-repo/semantics/openAccess  
dc.rights.uri
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/  
dc.subject
Anti-Proliferative  
dc.subject
Endophytic  
dc.subject
Hawaii  
dc.subject
Lactam-Isochromanone  
dc.subject
Nmr  
dc.subject
Nmr Calculations  
dc.subject.classification
Otras Ciencias Químicas  
dc.subject.classification
Ciencias Químicas  
dc.subject.classification
CIENCIAS NATURALES Y EXACTAS  
dc.title
Sphaerialactonam, a γ-lactam–isochromanone from the Hawaiian endophytic fungus Paraphaeosphaeria sp. FT462  
dc.type
info:eu-repo/semantics/article  
dc.type
info:ar-repo/semantics/artículo  
dc.type
info:eu-repo/semantics/publishedVersion  
dc.date.updated
2018-07-26T14:01:33Z  
dc.journal.volume
58  
dc.journal.number
13  
dc.journal.pagination
1330-1333  
dc.journal.pais
Estados Unidos  
dc.journal.ciudad
Nueva York  
dc.description.fil
Fil: Huang, Peng. University Of Hawaii At Hilo; Estados Unidos. Anhui University of Chinese Medicine; China  
dc.description.fil
Fil: Li, Chunshun. University Of Hawaii At Hilo; Estados Unidos. University of Hawaii Cancer Center; Estados Unidos  
dc.description.fil
Fil: Sarotti, Ariel Marcelo. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Rosario. Instituto de Química Rosario. Universidad Nacional de Rosario. Facultad de Ciencias Bioquímicas y Farmacéuticas. Instituto de Química Rosario; Argentina  
dc.description.fil
Fil: Turkson, James. University of Hawaii Cancer Center; Estados Unidos  
dc.description.fil
Fil: Cao, Shugeng. University Of Hawaii At Hilo; Estados Unidos. University of Hawaii Cancer Center; Estados Unidos  
dc.journal.title
Tetrahedron Letters  
dc.relation.alternativeid
info:eu-repo/semantics/altIdentifier/doi/https://dx.doi.org/10.1016/j.tetlet.2017.02.052  
dc.relation.alternativeid
info:eu-repo/semantics/altIdentifier/url/https://www.sciencedirect.com/science/article/pii/S0040403917302319  

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