Artículo
Novel application of HKUST-1 metal-organic framework as antifungal: Biological tests and physicochemical characterizations
Chiericatti, Carolina; Basilico, Juan Carlos; Zapata de Basilico, Maria de la Luz; Zamaro, Juan Manuel
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Fecha de publicación:
06/2012
Editorial:
Elsevier Science
Revista:
Microporous and Mesoporous Materials
ISSN:
1387-1811
Idioma:
Inglés
Tipo de recurso:
Artículo publicado
Clasificación temática:
Resumen
The HKUST-1 metal–organic framework (MOF) was successfully applied as a biocidal material against representative yeast and mold. The synthesized MOF showed a strong antifungal effect against Saccharomyces cerevisiae for which the growth was completely inhibited, whereas the growth of Geotrichum candidum was reduced from 6.16 to 1.29 CFU mL−1. The antifungal action was related to copper ions released into the culture medium due to a progressive degradation of the crystalline structure of the material that involved the formation of surface extra-framework Cu(I). This study shows the potential of using copper-based metal–organic frameworks for a controlled release of biologically active copper ions.
Palabras clave:
Metal-Organic Framework
,
Hkust-1
,
Antifungal Activity
,
Copper Release
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Articulos(INCAPE)
Articulos de INST.DE INVEST.EN CATALISIS Y PETROQUIMICA "ING. JOSE MIGUEL PARERA"
Articulos de INST.DE INVEST.EN CATALISIS Y PETROQUIMICA "ING. JOSE MIGUEL PARERA"
Citación
Chiericatti, Carolina; Basilico, Juan Carlos; Zapata de Basilico, Maria de la Luz; Zamaro, Juan Manuel; Novel application of HKUST-1 metal-organic framework as antifungal: Biological tests and physicochemical characterizations; Elsevier Science; Microporous and Mesoporous Materials; 162; 6-2012; 60-63
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