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dc.contributor.author
Villena, Julio Cesar
dc.contributor.author
Oliveira, María Leonor S.
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Ferreira, Patricia D.
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Salva, Maria Susana
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Alvarez, Gladis Susana
dc.date.available
2018-07-16T13:52:39Z
dc.date.issued
2011-11-25
dc.identifier.citation
Villena, Julio Cesar; Oliveira, María Leonor S.; Ferreira, Patricia D.; Salva, Maria Susana; Alvarez, Gladis Susana; Lactic acid bacteria in the prevention of pneumococcal respiratory infection: Future opportunities and challenges; Elsevier Science; International Immunopharmacology; 11; 11; 25-11-2011; 1633-1645
dc.identifier.issn
1567-5769
dc.identifier.uri
http://hdl.handle.net/11336/52135
dc.description.abstract
Lactic acid bacteria (LAB) are technologically and commercially important and have various beneficial effects on human health. Several studies have demonstrated that certain LAB strains can exert their beneficial effect on the host through their immunomudulatory activity. Although most research concerning LAB-mediated enhanced immune protection is focused on gastrointestinal tract pathogens, recent studies have centered on whether these immunobiotics might sufficiently stimulate the common mucosal immune system to provide protection to other mucosal sites as well. In this sense, LAB have been used for the development of probiotic foods with the ability to stimulate respiratory immunity, which would increase resistance to infections, even in immunocompromised hosts. On the other hand, the advances in the molecular biology of LAB have enabled the development of recombinant strains expressing antigens from respiratory pathogens that have proved effective to induce protective immunity. In this review we examine the current scientific literature concerning the use of LAB strains to prevent respiratory infections. In particular, we have focused on the works that deal with the capacity of probiotic and recombinant LAB to improve the immune response against Streptococcus pneumoniae. Research from the last decade demonstrates that LAB represent a promising resource for the development of prevention strategies against respiratory infections that could be effective tools for medical application.
dc.format
application/pdf
dc.language.iso
eng
dc.publisher
Elsevier Science
dc.rights
info:eu-repo/semantics/restrictedAccess
dc.rights.uri
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
dc.subject
Adjuvant
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Immunocompromised Hosts
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Lactic Acid Bacteria
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Respiratory Infection
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Streptococcus Pneumoniae
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Vaccine
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Inmunología
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Medicina Básica
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CIENCIAS MÉDICAS Y DE LA SALUD
dc.title
Lactic acid bacteria in the prevention of pneumococcal respiratory infection: Future opportunities and challenges
dc.type
info:eu-repo/semantics/article
dc.type
info:ar-repo/semantics/artículo
dc.type
info:eu-repo/semantics/publishedVersion
dc.date.updated
2018-04-16T14:27:47Z
dc.identifier.eissn
1878-1705
dc.journal.volume
11
dc.journal.number
11
dc.journal.pagination
1633-1645
dc.journal.pais
Países Bajos
dc.journal.ciudad
Amsterdam
dc.description.fil
Fil: Villena, Julio Cesar. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Tucumán. Centro de Referencia para Lactobacilos; Argentina
dc.description.fil
Fil: Oliveira, María Leonor S.. Instituto Butantan. Centro de Biotecnología; Brasil
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Fil: Ferreira, Patricia D.. Instituto Butantan. Centro de Biotecnología; Brasil
dc.description.fil
Fil: Salva, Maria Susana. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Tucumán. Centro de Referencia para Lactobacilos; Argentina
dc.description.fil
Fil: Alvarez, Gladis Susana. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Tucumán. Centro de Referencia para Lactobacilos; Argentina
dc.journal.title
International Immunopharmacology
dc.relation.alternativeid
info:eu-repo/semantics/altIdentifier/doi/http://dx.doi.org/10.1016/j.intimp.2011.06.004
dc.relation.alternativeid
info:eu-repo/semantics/altIdentifier/url/https://www.sciencedirect.com/science/article/pii/S1567576911002530


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