Repositorio Institucional
Repositorio Institucional
CONICET Digital
  • Inicio
  • EXPLORAR
    • AUTORES
    • DISCIPLINAS
    • COMUNIDADES
  • Estadísticas
  • Novedades
    • Noticias
    • Boletines
  • Ayuda
    • General
    • Datos de investigación
  • Acerca de
    • CONICET Digital
    • Equipo
    • Red Federal
  • Contacto
JavaScript is disabled for your browser. Some features of this site may not work without it.
  • INFORMACIÓN GENERAL
  • RESUMEN
  • ESTADISTICAS
 
Artículo

The native fruit geoffroea decorticans from arid northern Chile: phenolic composition, antioxidant activities and in vitro inhibition of pro-inflammatory and metabolic syndrome-associated enzymes

Jiménez Aspee, Felipe; Theoduloz, Cristina; Soriano, María del Pilar C.; Ugalde Arbizu, Maider; Alberto, Maria RosaIcon ; Zampini, Iris CatianaIcon ; Isla, Maria InesIcon ; Simirgiotis, Mario J.; Schmeda Hirschmann, Guillermo
Fecha de publicación: 09/2017
Editorial: Molecular Diversity Preservation International
Revista: Molecules
ISSN: 1420-3049
Idioma: Inglés
Tipo de recurso: Artículo publicado
Clasificación temática:
Otras Ciencias Biológicas

Resumen

The native tree Geoffroea decorticans (cha ar) grows in the arid lands of northern Chile. It has been used as a food plant since prehistoric times. Phenolic-enriched extracts (PEEs) of Chilean cha ar fruits were assessed for their chemical composition, antioxidant properties and inhibition of pro-inflammatory and metabolic syndrome-associated enzymes. Phenolic profiles were determined by HPLC-DAD-MS/MS. The PEEs of G. decorticans showed a strong effect towards the enzymes COX-1/COX-2, with inhibition percentages ranging from inactive to 92.1% and inactive to 76.0% at 50 µg PEE/mL, respectively. The IC50 values of the PEEs towards lipoxygenase and phospholipase A2 inhibitory activity were between 43.6–96.8 and 98.9–156.0 µg PEE/mL, respectively. Samples inhibited α-glucosidase (IC50 0.8–7.3 µg PEE/mL) and lipase (9.9 to 100 µg PEE/mL). However, samples did not inhibit α-amylase. The HPLC-DAD-MS analysis of the PEEs allowed the tentative identification of 53 compounds, mainly flavonol glycosides and procyanidins. The procyanidin content of the Chilean G. decorticans pulp was positively correlated with the antioxidant activity and the inhibition of the enzyme α-glucosidase. These results indicate that the Chilean cha ar fruit contains bioactive polyphenols with functional properties.
Palabras clave: Anti-Inflammatory Activity , Antioxidant Capacity , Geoffroea Decorticans , Hplc-Dad-Esi-Ms , Metabolic Syndrome-Associated Enzymes , Phenolic Composition
Ver el registro completo
 
Archivos asociados
Thumbnail
 
Tamaño: 1.430Mb
Formato: PDF
.
Descargar
Licencia
info:eu-repo/semantics/openAccess Excepto donde se diga explícitamente, este item se publica bajo la siguiente descripción: Creative Commons Attribution 2.5 Unported (CC BY 2.5)
Identificadores
URI: http://hdl.handle.net/11336/50654
DOI: http://dx.doi.org/10.3390/molecules22091565
URL: http://www.mdpi.com/1420-3049/22/9/1565
Colecciones
Articulos(INQUINOA)
Articulos de INST.DE QUIMICA DEL NOROESTE
Citación
Jiménez Aspee, Felipe; Theoduloz, Cristina; Soriano, María del Pilar C.; Ugalde Arbizu, Maider; Alberto, Maria Rosa; et al.; The native fruit geoffroea decorticans from arid northern Chile: phenolic composition, antioxidant activities and in vitro inhibition of pro-inflammatory and metabolic syndrome-associated enzymes; Molecular Diversity Preservation International; Molecules; 22; 9; 9-2017; 1-18; 1565
Compartir
Altmétricas
 

Enviar por e-mail
Separar cada destinatario (hasta 5) con punto y coma.
  • Facebook
  • X Conicet Digital
  • Instagram
  • YouTube
  • Sound Cloud
  • LinkedIn

Los contenidos del CONICET están licenciados bajo Creative Commons Reconocimiento 2.5 Argentina License

https://www.conicet.gov.ar/ - CONICET

Inicio

Explorar

  • Autores
  • Disciplinas
  • Comunidades

Estadísticas

Novedades

  • Noticias
  • Boletines

Ayuda

Acerca de

  • CONICET Digital
  • Equipo
  • Red Federal

Contacto

Godoy Cruz 2290 (C1425FQB) CABA – República Argentina – Tel: +5411 4899-5400 repositorio@conicet.gov.ar
TÉRMINOS Y CONDICIONES