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dc.contributor.author
Leon, Ignacio Esteban  
dc.contributor.author
Etcheverry, Susana Beatriz  
dc.contributor.author
Baran, Enrique José  
dc.date.available
2018-06-26T22:28:48Z  
dc.date.issued
2015-04  
dc.identifier.citation
Leon, Ignacio Esteban; Etcheverry, Susana Beatriz; Baran, Enrique José; Cytotoxicity action of an oxidovanadium(IV)-DPPZ complex on MG-63 human osteosarcoma cell line; Trade Science Journals; BioTechnology, An Indian Journal; 11; 12; 4-2015; 465-468  
dc.identifier.issn
0974-7435  
dc.identifier.uri
http://hdl.handle.net/11336/50200  
dc.description.abstract
The cytotoxicity activity of the recently reported [VO(H2O) 2(SO4)dppz]2H2O complex (dppz = dipyrido[3,2-a:2í,3í- c]phenazine) on MG-63 human osteosarcoma cell line was investigated. It was found that it caused a concentration related inhibitory effect in the concentration range between 5 and 25 µM and diminished the cell viability ca. 40% in the range from 25 to 100 ÏM, without dose/response effects in this range. These biological effects are, in general, similar to those previously reported for the related [VO(ODA)dppz].3H2O (ODA = dianion of oxodiacetic acid) and [VO(ODA)(phen)].1.5H2O (phen = o- phenanthroline) complexes. The importance of the presence of DNAintercalating ligands in these complexes is emphasized.  
dc.format
application/pdf  
dc.language.iso
eng  
dc.publisher
Trade Science Journals  
dc.rights
info:eu-repo/semantics/openAccess  
dc.rights.uri
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/  
dc.subject
Oxidovanadium(Iv)  
dc.subject
Dppz  
dc.subject
Metallointercalators  
dc.subject
Human Osteosarcoma Cell Line  
dc.subject.classification
Otras Ciencias Químicas  
dc.subject.classification
Ciencias Químicas  
dc.subject.classification
CIENCIAS NATURALES Y EXACTAS  
dc.title
Cytotoxicity action of an oxidovanadium(IV)-DPPZ complex on MG-63 human osteosarcoma cell line  
dc.type
info:eu-repo/semantics/article  
dc.type
info:ar-repo/semantics/artículo  
dc.type
info:eu-repo/semantics/publishedVersion  
dc.date.updated
2018-06-12T13:30:00Z  
dc.journal.volume
11  
dc.journal.number
12  
dc.journal.pagination
465-468  
dc.journal.pais
India  
dc.description.fil
Fil: Leon, Ignacio Esteban. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - La Plata. Centro de Química Inorgánica ; Argentina  
dc.description.fil
Fil: Etcheverry, Susana Beatriz. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - La Plata. Centro de Química Inorgánica ; Argentina  
dc.description.fil
Fil: Baran, Enrique José. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - La Plata. Centro de Química Inorgánica ; Argentina  
dc.journal.title
BioTechnology, An Indian Journal  
dc.relation.alternativeid
info:eu-repo/semantics/altIdentifier/url/http://www.tsijournals.com/abstract/cytotoxicity-action-of-an-oxidovanadiumivdppz-complex-on-mg63-human-osteosarcoma-cell-line-2208.html  

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