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dc.contributor.author
García Mitacek, María Carla  
dc.contributor.author
Praderio, Romina Gisele  
dc.contributor.author
Stornelli, María Alejandra  
dc.contributor.author
de la Sota, Rodolfo Luzbel  
dc.contributor.author
Stornelli, María Alejandra  
dc.date.available
2018-06-22T19:20:29Z  
dc.date.issued
2017-04  
dc.identifier.citation
García Mitacek, María Carla; Praderio, Romina Gisele; Stornelli, María Alejandra; de la Sota, Rodolfo Luzbel; Stornelli, María Alejandra; Prostaglandin synthesis enzymes' gene transcription in bitches with endometritis; Wiley Blackwell Publishing, Inc; Reproduction in Domestic Animals; 52; 4-2017; 298-302  
dc.identifier.issn
0936-6768  
dc.identifier.uri
http://hdl.handle.net/11336/49713  
dc.description.abstract
Endometritis is a major cause of infertility in many domestic species. However, until now the pathogenesis of the endometritis in the bitch is unclear. The aim of this study was to evaluate the gene transcription pattern of prostaglandin (PG) synthesis enzymes (cyclooxygenase [COX2], PTGES-1 and PGFS) in the endometrium of bitches with or without endometritis. Thirty mixed breed bitches in dioestrus, aged between 1 and 5 years, and weighing between 10 and 30 kg were used. After ovariohysterectomy (OVX), uterine biopsy samples were collected from the middle part of both horns. Then, endometrial epithelium was collected using the cytobrush method and mRNA analysis was performed by real-time RT-PCR. Data were analysed with Kruskal–Wallis anova using the sas® software. Uterine condition was identified by endometrial biopsies (normal endometria [n = 11; NE], acute endometritis [n = 10; AE] and chronic endometritis [n = 9; CE]). The COX2, PTGES-1 and PGFS/AKR1C3 mRNA expression in bitches with and without endometritis was similar. Except for PGFS/AKR1C3, gene transcription of COX2 and PTGES-1 was significantly increased in AE compared with CE. In addition, COX2 gene transcription was significantly increased in AE compared with NE. In contrast, no differences were found for COX2, PTGES-1 and PGFS/AKR1C3 mRNA expression in the samples of NE compared with CE.  
dc.format
application/pdf  
dc.language.iso
eng  
dc.publisher
Wiley Blackwell Publishing, Inc  
dc.rights
info:eu-repo/semantics/openAccess  
dc.rights.uri
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/  
dc.subject
Bitch  
dc.subject
Utero  
dc.subject
Endometrio  
dc.subject.classification
Ciencias Veterinarias  
dc.subject.classification
Ciencias Veterinarias  
dc.subject.classification
CIENCIAS AGRÍCOLAS  
dc.title
Prostaglandin synthesis enzymes' gene transcription in bitches with endometritis  
dc.type
info:eu-repo/semantics/article  
dc.type
info:ar-repo/semantics/artículo  
dc.type
info:eu-repo/semantics/publishedVersion  
dc.date.updated
2018-06-21T13:00:06Z  
dc.journal.volume
52  
dc.journal.pagination
298-302  
dc.journal.pais
Reino Unido  
dc.journal.ciudad
Londres  
dc.description.fil
Fil: García Mitacek, María Carla. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina. Universidad Nacional de la Plata. Facultad de Ciencias Veterinarias. Departamento de Clínica. Cátedra de Reproducción Animal; Argentina  
dc.description.fil
Fil: Praderio, Romina Gisele. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina. Universidad Nacional de la Plata. Facultad de Ciencias Veterinarias. Departamento de Clínica. Cátedra de Reproducción Animal; Argentina  
dc.description.fil
Fil: Stornelli, María Alejandra. Universidad Nacional de la Plata. Facultad de Ciencias Veterinarias. Departamento de Clínica. Cátedra de Reproducción Animal; Argentina  
dc.description.fil
Fil: de la Sota, Rodolfo Luzbel. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina. Universidad Nacional de la Plata. Facultad de Ciencias Veterinarias. Departamento de Clínica. Cátedra de Reproducción Animal; Argentina  
dc.description.fil
Fil: Stornelli, María Alejandra. Universidad Nacional de la Plata. Facultad de Ciencias Veterinarias. Departamento de Clínica. Cátedra de Reproducción Animal; Argentina  
dc.journal.title
Reproduction in Domestic Animals  
dc.relation.alternativeid
info:eu-repo/semantics/altIdentifier/doi/https://dx.doi.org/10.1111/rda.12950  
dc.relation.alternativeid
info:eu-repo/semantics/altIdentifier/url/https://onlinelibrary.wiley.com/doi/abs/10.1111/rda.12950