Artículo
Orcokinin neuropeptides regulate ecdysis in the hemimetabolous insect Rhodnius prolixus
Wulff, Juan Pedro
; Sierra, Ivana Samanta
; Sterkel, Marcos
; Holtof, Michiel; Van Wielendaele, Pieter; Francini, Flavio
; Vanden Broeck, Jozef; Ons, Sheila
Fecha de publicación:
02/2017
Editorial:
Elsevier
Revista:
Insect Biochemistry And Molecular Biology
ISSN:
0965-1748
e-ISSN:
1879-0240
Idioma:
Inglés
Tipo de recurso:
Artículo publicado
Clasificación temática:
Resumen
To grow and develop insects must undergo ecdysis. During this process, the individual sheds the old cuticle to emerge as the following developmental stage. During ecdysis, different programed behaviors are regulated by neuropeptidergic pathways. In general, components of these pathways are better characterized in crustacean and holometabolous insects than in hemimetabola. In insects, the orkoninin gene produces two different neuropeptide precursors by alternative splicing: orcokinin A and orcokinin B. Although orcokinins are well conserved in insect species, their physiological role remains elusive. Here we describe a new splicing variant of the orcokinin gene in the hemimetabolous triatomine Rhodnius prolixus. We further analyze the expression pattern and the function of the alternatively spliced RhoprOK transcripts by means of immunohistochemistry and RNAi-mediated gene silencing. Our results indicate that orkoninis play an essential role in the peptidergic signaling pathway regulating ecdysis in the hemimetabolous insect Rhodnius prolixus.
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Licencia
Identificadores
Colecciones
Articulos(CCT - LA PLATA)
Articulos de CTRO.CIENTIFICO TECNOL.CONICET - LA PLATA
Articulos de CTRO.CIENTIFICO TECNOL.CONICET - LA PLATA
Articulos(CENEXA)
Articulos de CENTRO DE ENDOCRINOLOGIA EXP.Y APLICADA (I)
Articulos de CENTRO DE ENDOCRINOLOGIA EXP.Y APLICADA (I)
Citación
Wulff, Juan Pedro; Sierra, Ivana Samanta; Sterkel, Marcos; Holtof, Michiel; Van Wielendaele, Pieter; et al.; Orcokinin neuropeptides regulate ecdysis in the hemimetabolous insect Rhodnius prolixus; Elsevier; Insect Biochemistry And Molecular Biology; 81; 2-2017; 91-102
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