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dc.contributor.author
Mongiat, Lucas Alberto
dc.contributor.author
Schinder, Alejandro Fabián
dc.date.available
2018-06-15T14:13:23Z
dc.date.issued
2011-03
dc.identifier.citation
Mongiat, Lucas Alberto; Schinder, Alejandro Fabián; Adult neurogenesis and the plasticity of the dentate gyrus network; Wiley Blackwell Publishing, Inc; European Journal of Neurosciences; 33; 6; 3-2011; 1055-1061
dc.identifier.issn
0953-816X
dc.identifier.uri
http://hdl.handle.net/11336/48757
dc.description.abstract
The granule cell layer (GCL) of the dentate gyrus contains neurons generated during embryonic, early postnatal and adult life. During adulthood there is a continuous production of neuronal cohorts that develop and functionally integrate in the preexisting circuits. This morphogenic process generates a stratified GCL, with the outermost layers containing dentate granule cells (DGCs) generated during perinatal life, and the innermost layers containing adult-born DGCs. In this review we analyse the functional profile of the different neuronal populations of the GCL, with an emphasis on adult-born neurons as they develop, mature and integrate in the dentate gyrus network. We focus on the contribution of adult-born neurons to activity-dependent synaptic modification in the dentate gyrus and, in turn, discuss how network activity modulates integration and survival of new neurons.
dc.format
application/pdf
dc.language.iso
eng
dc.publisher
Wiley Blackwell Publishing, Inc
dc.rights
info:eu-repo/semantics/openAccess
dc.rights.uri
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
dc.subject
Hippocampus
dc.subject
Adult Neurogenesis
dc.subject
Synaptic Plasticity
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Neuronal Development
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Otras Ciencias Biológicas
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Ciencias Biológicas
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CIENCIAS NATURALES Y EXACTAS
dc.title
Adult neurogenesis and the plasticity of the dentate gyrus network
dc.type
info:eu-repo/semantics/article
dc.type
info:ar-repo/semantics/artículo
dc.type
info:eu-repo/semantics/publishedVersion
dc.date.updated
2018-06-13T15:11:37Z
dc.identifier.eissn
1460-9568
dc.journal.volume
33
dc.journal.number
6
dc.journal.pagination
1055-1061
dc.journal.pais
Reino Unido
dc.journal.ciudad
Oxford
dc.description.fil
Fil: Mongiat, Lucas Alberto. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Parque Centenario. Instituto de Investigaciones Bioquímicas de Buenos Aires. Fundación Instituto Leloir. Instituto de Investigaciones Bioquímicas de Buenos Aires; Argentina
dc.description.fil
Fil: Schinder, Alejandro Fabián. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Parque Centenario. Instituto de Investigaciones Bioquímicas de Buenos Aires. Fundación Instituto Leloir. Instituto de Investigaciones Bioquímicas de Buenos Aires; Argentina
dc.journal.title
European Journal of Neurosciences
dc.relation.alternativeid
info:eu-repo/semantics/altIdentifier/doi/doi:10.1111/j.1460-9568.2011.07603.x
dc.relation.alternativeid
info:eu-repo/semantics/altIdentifier/url/https://www.ncbi.nlm.nih.gov/pubmed/21395848
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