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dc.contributor.author Stringa, Pablo Luis
dc.contributor.author Andrés Moreno, Ane M.
dc.contributor.author Lausada, Natalia Raquel
dc.contributor.author Pastor Oliver, Cristina
dc.contributor.author Abate, Juan C.
dc.contributor.author Vecchio, Leandro
dc.contributor.author Rumbo, Martín
dc.contributor.author Navarro Zorraquino, Marta
dc.contributor.author Hernández Oliveros, Francisco
dc.contributor.author Gondolesi, Gabriel Eduardo
dc.date.available 2018-06-12T20:12:03Z
dc.date.issued 2016-12
dc.identifier.citation Stringa, Pablo Luis; Andrés Moreno, Ane M.; Lausada, Natalia Raquel; Pastor Oliver, Cristina; Abate, Juan C.; et al.; Small bowel transplantation in rats, a multicenter experience summarizing the pitfalls to be overcome; Open Access Text; Transplantation Open; 2; 1; 12-2016; 1-7
dc.identifier.issn 2399-5289
dc.identifier.uri http://hdl.handle.net/11336/48434
dc.description.abstract Small Bowel transplantation in rats is a highly complex microsurgical procedure because several technical complications may lead to recipient mortality and transplant failure. Our aim was to report the most common complications associated with orthotopic and heterotopic intestinal transplantation in rats in order to identify the “pitfalls” of the procedure and prevent them. A retrospective multicenter study was performed. All participant centers have established rodent transplant procedures and trained surgeons. Two hundred ninety-three complications from 264 unsuccessful intestinal transplants were reported, representing an overall failure rate of 15% of the procedures performed. Recipient complications were most frequent than donor (257 vs. 36 p<0.0001). Excessive surgical time (11/36); severe hemorrhage (12/36) and inappropriate infusion of the preservation solution in the intestinal graft (11/36) were the most common donor complications. Arterial anastomosis bleeding (50/257), venous anastomosis bleeding (35/257) and portal vein stenosis (26/257) were the most common intraoperative complications in the recipient. To maximize success rate, surgeons should optimize time and avoid bleeding during graft dissection in the donor surgery. After performing a bloodless vascular anastomosis an adequate post-operative management of the animal is mandatory to guarantee survival.
dc.format application/pdf
dc.language.iso eng
dc.publisher Open Access Text
dc.rights info:eu-repo/semantics/openAccess
dc.rights.uri https://creativecommons.org/licenses/by/2.5/ar/
dc.subject INTESTINAL TRANSPLANTATION
dc.subject SURGICAL COMPLIATIONS
dc.subject RATS
dc.subject MICROSURGERY
dc.subject.classification Inmunología
dc.subject.classification Medicina Básica
dc.subject.classification CIENCIAS MÉDICAS Y DE LA SALUD
dc.title Small bowel transplantation in rats, a multicenter experience summarizing the pitfalls to be overcome
dc.type info:eu-repo/semantics/article
dc.type info:ar-repo/semantics/artículo
dc.type info:eu-repo/semantics/publishedVersion
dc.date.updated 2018-06-06T19:47:29Z
dc.journal.volume 2
dc.journal.number 1
dc.journal.pagination 1-7
dc.journal.pais Estados Unidos
dc.description.fil Fil: Stringa, Pablo Luis. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Houssay. Instituto de Medicina Traslacional, Trasplante y Bioingeniería. Fundación Favaloro. Instituto de Medicina Traslacional, Trasplante y Bioingeniería; Argentina. Universidad Nacional de la Plata. Facultad de Ciencias Médicas. Laboratorio de Transplante de Órganos; Argentina
dc.description.fil Fil: Andrés Moreno, Ane M.. La Paz University Hospital; España
dc.description.fil Fil: Lausada, Natalia Raquel. Universidad Nacional de la Plata. Facultad de Ciencias Médicas. Laboratorio de Transplante de Órganos; Argentina
dc.description.fil Fil: Pastor Oliver, Cristina. Biomedical Research Center from Aragón; España
dc.description.fil Fil: Abate, Juan C.. Universidad Nacional de la Plata. Facultad de Ciencias Médicas. Laboratorio de Transplante de Órganos; Argentina
dc.description.fil Fil: Vecchio, Leandro. Universidad Nacional de la Plata. Facultad de Ciencias Médicas. Laboratorio de Transplante de Órganos; Argentina
dc.description.fil Fil: Rumbo, Martín. Comisión Nacional de Investigación Científica y Tecnológica; Chile. Universidad Nacional de la Plata. Facultad de Ciencias Médicas. Laboratorio de Transplante de Órganos; Argentina
dc.description.fil Fil: Navarro Zorraquino, Marta. Biomedical Research Center from Aragón; España
dc.description.fil Fil: Hernández Oliveros, Francisco. La Paz University Hospital; España
dc.description.fil Fil: Gondolesi, Gabriel Eduardo. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Houssay. Instituto de Medicina Traslacional, Trasplante y Bioingeniería. Fundación Favaloro. Instituto de Medicina Traslacional, Trasplante y Bioingeniería; Argentina. Universidad Nacional de la Plata. Facultad de Ciencias Médicas. Laboratorio de Transplante de Órganos; Argentina
dc.journal.title Transplantation Open
dc.relation.alternativeid info:eu-repo/semantics/altIdentifier/url/http://www.oatext.com/Small-bowel-transplantation-in-rats,-A-multicenter-experience-summarizing-the-pitfalls-to-be-overcome.php
dc.relation.alternativeid info:eu-repo/semantics/altIdentifier/doi/http://dx.doi.org/10.15761/TiT.1000217
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info:eu-repo/semantics/openAccess Excepto donde se diga explícitamente, este item se publica bajo la siguiente descripción: Creative Commons Attribution 2.5 Unported (CC BY 2.5)