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dc.contributor.author Martí, Luis Enrique
dc.contributor.author Sanchez, Laura Mabel
dc.contributor.author Climent, Maria José
dc.contributor.author Corma, Avelino
dc.contributor.author Iborra, Sara
dc.contributor.author Romanelli, Gustavo Pablo
dc.contributor.author Concepción, Patricia
dc.date.available 2018-06-12T17:35:12Z
dc.date.issued 2017-11-26
dc.identifier.citation Martí, Luis Enrique; Sanchez, Laura Mabel; Climent, Maria José; Corma, Avelino; Iborra, Sara; et al.; Chemoselective Reductive Heterocyclization by Controlling the Binomial Architecture of Metal Particles and Acid–Base Properties of the Support; American Chemical Society; ACS Catalysis; 7; 12; 26-11-2017; 8255-8262
dc.identifier.uri http://hdl.handle.net/11336/48359
dc.description.abstract 2,1-Benzisoxazoles have been selectively synthesized through reductive heterocyclization of 2-nitroacylarenes using Pt-supported nanoparticles. The reaction involves a cascade process in which the first step is the reduction of the nitro group into hydroxylamine followed by heterocyclization through the nucleophilic attack of the hydroxylamine group to the carbonyl of the acyl group and further dehydration. The reaction was performed on Pt/C, Pt/TiO2, and Pt/MgO using hydrogen as the reducing agent under mild reaction conditions. The results showed that Pt/MgO was the most active and selective catalyst. The study of the influence of the crystal size of the metal on the activity and selectivity, combined with the reaction mechanism examined by in situ Fourier transform infrared spectroscopy of the adsorbed reactant, showed that the maximum activity and selectivity to the target compound can be achieved by controlling the architecture of metal particles and acid-base properties of the support. The effect of temperature on selectivity, the stability of the Pt/MgO catalyst, and the scope of the reaction have been studied. Finally, reductive heterocyclization using different metals (Pd and Au) supported on MgO has also been performed.
dc.format application/pdf
dc.language.iso eng
dc.publisher American Chemical Society
dc.rights info:eu-repo/semantics/restrictedAccess
dc.rights.uri https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
dc.subject 2,1-BENZISOXAZOLE
dc.subject 2-NITROACYLARENES
dc.subject CASCADE PROCESS
dc.subject PT/MGO
dc.subject REDUCTIVE HETEROCYCLIZATION
dc.subject.classification Otras Ingeniería Química
dc.subject.classification Ingeniería Química
dc.subject.classification INGENIERÍAS Y TECNOLOGÍAS
dc.subject.classification Otras Ciencias Químicas
dc.subject.classification Ciencias Químicas
dc.subject.classification CIENCIAS NATURALES Y EXACTAS
dc.title Chemoselective Reductive Heterocyclization by Controlling the Binomial Architecture of Metal Particles and Acid–Base Properties of the Support
dc.type info:eu-repo/semantics/article
dc.type info:ar-repo/semantics/artículo
dc.type info:eu-repo/semantics/publishedVersion
dc.date.updated 2018-04-16T13:58:20Z
dc.identifier.eissn 2155-5435
dc.journal.volume 7
dc.journal.number 12
dc.journal.pagination 8255-8262
dc.journal.pais Estados Unidos
dc.description.fil Fil: Martí, Luis Enrique. Universidad Politécnica de Valencia; España
dc.description.fil Fil: Sanchez, Laura Mabel. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - La Plata. Centro de Investigación y Desarrollo en Ciencias Aplicadas "Dr. Jorge J. Ronco". Universidad Nacional de la Plata. Facultad de Ciencias Exactas. Centro de Investigación y Desarrollo en Ciencias Aplicadas; Argentina
dc.description.fil Fil: Climent, Maria José. Universidad Politécnica de Valencia; España
dc.description.fil Fil: Corma, Avelino. Universidad Politécnica de Valencia; España
dc.description.fil Fil: Iborra, Sara. Universidad Politécnica de Valencia; España
dc.description.fil Fil: Romanelli, Gustavo Pablo. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - La Plata. Centro de Investigación y Desarrollo en Ciencias Aplicadas "Dr. Jorge J. Ronco". Universidad Nacional de la Plata. Facultad de Ciencias Exactas. Centro de Investigación y Desarrollo en Ciencias Aplicadas; Argentina
dc.description.fil Fil: Concepción, Patricia. Universidad Politécnica de Valencia; España
dc.journal.title ACS Catalysis
dc.relation.alternativeid info:eu-repo/semantics/altIdentifier/doi/https://dx.doi.org/10.1021/acscatal.7b01841
dc.relation.alternativeid info:eu-repo/semantics/altIdentifier/url/https://pubs.acs.org/toc/accacs/7/12#Articles
dc.conicet.fuente Elsevier


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info:eu-repo/semantics/restrictedAccess Excepto donde se diga explícitamente, este item se publica bajo la siguiente descripción: Creative Commons Attribution-NonCommercial-ShareAlike 2.5 Unported (CC BY-NC-SA 2.5)