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dc.contributor.author
Fernandez, María Elena
dc.contributor.author
Loaiza Echeverri, A.M.
dc.contributor.author
Henry, M.
dc.contributor.author
Drummond, M
dc.contributor.author
Andrade de Oliveira, DA
dc.contributor.author
Demyda-Peyrás, Sebastian
dc.contributor.author
Cunha Cardoso, D
dc.contributor.author
Giovambattista, Guillermo
dc.contributor.author
Liron, Juan Pedro
dc.date.available
2018-06-11T20:30:24Z
dc.date.issued
2017-10
dc.identifier.citation
Fernandez, María Elena; Loaiza Echeverri, A.M.; Henry, M.; Drummond, M; Andrade de Oliveira, DA; et al.; Bovine thyroglobulin gene polymorphisms and their association with sexual precocity in Guzerat bulls; Wiley Blackwell Publishing, Inc; Reproduction in Domestic Animals; 52; 5; 10-2017; 911-913
dc.identifier.issn
0936-6768
dc.identifier.uri
http://hdl.handle.net/11336/48165
dc.description.abstract
Puberty is a stage of sexual development determined by the interaction of environmental factors and genetic mechanisms. Among them, thyroid function plays a key role in sexual development and spermatogenic function and is under the control of several genes, including the well-described thyroglobulin gene (TG). Previous reports have shown genetic association between thyroid function and selected single nucleotide polymorphisms (SNPs) in taurine cattle. Therefore, the identification of genetic mechanisms involved in the regulation of this trait can assist with the selection for early pubertal bulls, thus improving genetic progress in livestock breeding. The aim of this study was to validate the association between TG SNPs and age at puberty in zebuine bulls. Three SNPs (rs110406764, rs109662686, rs109057985) were genotyped in 159 Guzerat animals using SEQUENOM technology. Results showed a significant association (p < .05) between the studied SNPs and puberty age, in agreement with our previous reports in a taurine breed. Interestingly, allele frequencies were different from those already reported, being GAT the most favourable allele for age at puberty in Guzerat (94.4 days lower). Overall, our findings corroborate previous reports and reinforce the importance of genetic influence in the regulation of sexualdevelopment and puberty through a thyroid pathway in zebuine cattle.
dc.format
application/pdf
dc.language.iso
eng
dc.publisher
Wiley Blackwell Publishing, Inc
dc.rights
info:eu-repo/semantics/restrictedAccess
dc.rights.uri
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
dc.subject
Tyroglobuline
dc.subject
Snp
dc.subject
Zebu Cattle
dc.subject.classification
Otras Biotecnología Agropecuaria
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Biotecnología Agropecuaria
dc.subject.classification
CIENCIAS AGRÍCOLAS
dc.title
Bovine thyroglobulin gene polymorphisms and their association with sexual precocity in Guzerat bulls
dc.type
info:eu-repo/semantics/article
dc.type
info:ar-repo/semantics/artículo
dc.type
info:eu-repo/semantics/publishedVersion
dc.date.updated
2018-06-11T14:28:27Z
dc.journal.volume
52
dc.journal.number
5
dc.journal.pagination
911-913
dc.journal.pais
Reino Unido
dc.journal.ciudad
Londres
dc.description.fil
Fil: Fernandez, María Elena. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico CONICET- La Plata. Instituto de Genética Veterinaria ; Argentina
dc.description.fil
Fil: Loaiza Echeverri, A.M.. Universidade Federal de Minas Gerais; Brasil
dc.description.fil
Fil: Henry, M.. Universidade Federal de Minas Gerais; Brasil
dc.description.fil
Fil: Drummond, M. Universidade Federal de Minas Gerais; Brasil
dc.description.fil
Fil: Andrade de Oliveira, DA. Universidade Federal de Minas Gerais; Brasil
dc.description.fil
Fil: Demyda-Peyrás, Sebastian. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico CONICET- La Plata. Instituto de Genética Veterinaria ; Argentina
dc.description.fil
Fil: Cunha Cardoso, D. Universidade Federal de Minas Gerais; Brasil
dc.description.fil
Fil: Giovambattista, Guillermo. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico CONICET- La Plata. Instituto de Genética Veterinaria ; Argentina
dc.description.fil
Fil: Liron, Juan Pedro. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico CONICET- La Plata. Instituto de Genética Veterinaria ; Argentina
dc.journal.title
Reproduction in Domestic Animals
dc.relation.alternativeid
info:eu-repo/semantics/altIdentifier/doi/https://dx.doi.org/10.1111/rda.12989
dc.relation.alternativeid
info:eu-repo/semantics/altIdentifier/url/https://onlinelibrary.wiley.com/doi/abs/10.1111/rda.12989
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