Mostrar el registro sencillo del ítem
dc.contributor.author
White, M.D.
dc.contributor.author
Bissiere, S.
dc.contributor.author
Alvarez, Yanina Daniela
dc.contributor.author
Plachta, N.
dc.date.available
2018-06-08T17:57:11Z
dc.date.issued
2016-05
dc.identifier.citation
White, M.D.; Bissiere, S.; Alvarez, Yanina Daniela; Plachta, N.; Mouse Embryo Compaction; Elsevier Academic Press Inc; Current Topics In Developmental Biology; 120; 5-2016; 235-258
dc.identifier.issn
0070-2153
dc.identifier.uri
http://hdl.handle.net/11336/47907
dc.description.abstract
Compaction is a critical first morphological event in the preimplantation development of the mammalian embryo. Characterized by the transformation of the embryo from a loose cluster of spherical cells into a tightly packed mass, compaction is a key step in the establishment of the first tissue-like structures of the embryo. Although early investigation of the mechanisms driving compaction implicated changes in cell?cell adhesion, recent work has identified essential roles for cortical tension and a compaction-specific class of filopodia. During the transition from 8 to 16 cells, as the embryo is compacting, it must also make fundamental decisions regarding cell position, polarity, and fate. Understanding how these and other processes are integrated with compaction requires further investigation. Emerging imaging-based techniques that enable quantitative analysis from the level of cell?cell interactions down to the level of individual regulatory molecules will provide a greater understanding of how compaction shapes the early mammalian embryo.
dc.format
application/pdf
dc.language.iso
eng
dc.publisher
Elsevier Academic Press Inc
dc.rights
info:eu-repo/semantics/openAccess
dc.rights.uri
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
dc.subject
Mouse Embryo Development
dc.subject
Compaction
dc.subject.classification
Otras Ciencias Biológicas
dc.subject.classification
Ciencias Biológicas
dc.subject.classification
CIENCIAS NATURALES Y EXACTAS
dc.title
Mouse Embryo Compaction
dc.type
info:eu-repo/semantics/article
dc.type
info:ar-repo/semantics/artículo
dc.type
info:eu-repo/semantics/publishedVersion
dc.date.updated
2018-06-01T13:55:45Z
dc.journal.volume
120
dc.journal.pagination
235-258
dc.journal.pais
Estados Unidos
dc.journal.ciudad
Burlington, MA, Estados Unidos
dc.description.fil
Fil: White, M.D.. Institute of Molecular and Cell Biology; Singapur
dc.description.fil
Fil: Bissiere, S.. Institute of Molecular and Cell Biology; Singapur
dc.description.fil
Fil: Alvarez, Yanina Daniela. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Ciudad Universitaria. Instituto de Física de Buenos Aires. Universidad de Buenos Aires. Facultad de Ciencias Exactas y Naturales. Instituto de Física de Buenos Aires; Argentina
dc.description.fil
Fil: Plachta, N.. Institute of Molecular and Cell Biology; Singapur
dc.journal.title
Current Topics In Developmental Biology
dc.relation.alternativeid
info:eu-repo/semantics/altIdentifier/url/https://www.sciencedirect.com/science/article/pii/S0070215316301028?via%3Dihub
dc.relation.alternativeid
info:eu-repo/semantics/altIdentifier/doi/http://dx.doi.org/10.1016/bs.ctdb.2016.04.005
Archivos asociados