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dc.contributor.author
Turk, Gabriela Julia Ana  
dc.contributor.author
Carobene, Mauricio  
dc.date.available
2018-06-06T14:32:54Z  
dc.date.issued
2015-03  
dc.identifier.citation
Turk, Gabriela Julia Ana; Carobene, Mauricio; Deciphering How HIV‐1 Intersubtype Recombination Shapes Viral Fitness and Disease Progression; Elsevier; EBioMedicine; 2; 3; 3-2015; 188-189  
dc.identifier.issn
2352-3964  
dc.identifier.uri
http://hdl.handle.net/11336/47455  
dc.description.abstract
Extreme genetic variability is the hallmark of HIV‐1 infection and itrepresents a major challenge for antiviral treatment and vaccine development.HIV‐1 group M dominates the global pandemic. This genetic diversity not only affects viral epidemiology but it is also linked to the mechanisms used by the virus to escape the patients´ natural humoral and cellular immune responses as well as antiretroviral drug´s action, thus precluding viral control. As a result, monitoring the genetic diversity of HIV‐1 and understanding its consequences onviral fitness is crucial to control the spread of the epidemic  
dc.format
application/pdf  
dc.language.iso
eng  
dc.publisher
Elsevier  
dc.rights
info:eu-repo/semantics/openAccess  
dc.rights.uri
https://creativecommons.org/licenses/by-nc-nd/2.5/ar/  
dc.subject
Hiv  
dc.subject
Recombination  
dc.subject
Fitness  
dc.subject
Disease  
dc.subject.classification
Otras Ciencias Biológicas  
dc.subject.classification
Ciencias Biológicas  
dc.subject.classification
CIENCIAS NATURALES Y EXACTAS  
dc.title
Deciphering How HIV‐1 Intersubtype Recombination Shapes Viral Fitness and Disease Progression  
dc.type
info:eu-repo/semantics/article  
dc.type
info:ar-repo/semantics/artículo  
dc.type
info:eu-repo/semantics/publishedVersion  
dc.date.updated
2018-06-06T13:37:08Z  
dc.journal.volume
2  
dc.journal.number
3  
dc.journal.pagination
188-189  
dc.journal.pais
Países Bajos  
dc.journal.ciudad
Amsterdan  
dc.description.fil
Fil: Turk, Gabriela Julia Ana. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Houssay. Instituto de Investigaciones Biomédicas en Retrovirus y Sida. Universidad de Buenos Aires. Facultad de Medicina. Instituto de Investigaciones Biomédicas en Retrovirus y Sida; Argentina  
dc.description.fil
Fil: Carobene, Mauricio. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Houssay. Instituto de Investigaciones Biomédicas en Retrovirus y Sida. Universidad de Buenos Aires. Facultad de Medicina. Instituto de Investigaciones Biomédicas en Retrovirus y Sida; Argentina  
dc.journal.title
EBioMedicine  
dc.relation.alternativeid
info:eu-repo/semantics/altIdentifier/doi/https://dx.doi.org/10.1016/j.ebiom.2015.02.011  
dc.relation.alternativeid
info:eu-repo/semantics/altIdentifier/url/https://www.sciencedirect.com/science/article/pii/S2352396415000596