Artículo
Partial molecular characterization of different proviral strains of bovine leukemia virus
Juliarena, Marcela Alicia
; Lendez, Pamela Anahí; Gutiérrez, Silvina Elena
; Forletti, Agustina
; Rensetti, Daniel Ernesto; Ceriani, Maria Carolina
Fecha de publicación:
01/2013
Editorial:
Springer
Revista:
Archives of Virology
ISSN:
0304-8608
Idioma:
Inglés
Tipo de recurso:
Artículo publicado
Clasificación temática:
Resumen
Bovine leukemia virus (BLV)-infected cattle were classified by their proviral load into low and high proviral load profiles (LPL and HPL, respectively). Blood from these animals was used to infect sheep to obtain multiple identical copies of integrated provirus. An env fragment of BLV was amplified from all infected sheep and sequenced. The sequences that were obtained were compared to already published BLV genome sequence, resulting in three clusters. Mutations could not be attributed to the passage of provirus from cattle to sheep and subsequent amplification and sequencing. The description of two different proviral load profiles, the association of the BoLA-DRB3.2*0902 allele with the LPL profile, the availability of complete BLV sequences, and the comparison of a variable region of the env gene from carefully characterized cattle are still not enough to explain the presence of animals in every herd that are resistant to BLV dissemination.
Palabras clave:
Bovine Leukemia Virus
,
Strains
,
Env Sequence
,
Low Proviral Load
Archivos asociados
Licencia
Identificadores
Colecciones
Articulos(CCT - TANDIL)
Articulos de CTRO CIENTIFICO TECNOLOGICO CONICET - TANDIL
Articulos de CTRO CIENTIFICO TECNOLOGICO CONICET - TANDIL
Articulos(CIVETAN)
Articulos de CENTRO DE INVESTIGACION VETERINARIA DE TANDIL
Articulos de CENTRO DE INVESTIGACION VETERINARIA DE TANDIL
Citación
Juliarena, Marcela Alicia; Lendez, Pamela Anahí; Gutiérrez, Silvina Elena; Forletti, Agustina; Rensetti, Daniel Ernesto; et al.; Partial molecular characterization of different proviral strains of bovine leukemia virus; Springer; Archives of Virology; 158; 1; 1-2013; 63-70
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