Artículo

The regulatory role of B cells in autoimmunity, infections and cancer: Perspectives beyond IL10 production

Gorosito Serran, MelisaIcon ; Fiocca Vernengo, FacundoIcon ; Beccaria, Cristian GabrielIcon ; Acosta Rodriguez, Eva VirginiaIcon ; Montes, Carolina LuciaIcon ; Gruppi, AdrianaIcon
Fecha de publicación: 11/2015
Editorial: Elsevier Science
Revista: FEBS Letters
ISSN: 0014-5793
e-ISSN: 1873-3468
Idioma: Inglés
Tipo de recurso: Artículo publicado
Clasificación temática:

Resumen

The term regulatory B cells (B regs) is ascribed to a heterogeneous population of B cells with the function of suppressing inflammatory responses. They have been described mainly during the last decade in the context of different immune-mediated diseases. Most of the work on B regs has been focused on IL-10-producing B cells. However, B cells can exert regulatory functions independently of IL-10 production. Here we discuss the phenotypes, development and effector mechanisms of B regs and advances in their role in autoimmunity, infections and cancer.
Palabras clave: B Cell , Autoimmunity , Regulation
 
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info:eu-repo/semantics/openAccess Excepto donde se diga explícitamente, este item se publica bajo la siguiente descripción: Creative Commons Attribution-NonCommercial-ShareAlike 2.5 Unported (CC BY-NC-SA 2.5)
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URI: http://hdl.handle.net/11336/46045
URL: https://bit.ly/2LoBgym
DOI: https://doi.org/10.1016/j.febslet.2015.08.048
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Articulos(CIBICI)
Articulos de CENTRO DE INV.EN BIOQUI.CLINICA E INMUNOLOGIA
Citación
Gorosito Serran, Melisa; Fiocca Vernengo, Facundo; Beccaria, Cristian Gabriel; Acosta Rodriguez, Eva Virginia; Montes, Carolina Lucia; et al.; The regulatory role of B cells in autoimmunity, infections and cancer: Perspectives beyond IL10 production; Elsevier Science; FEBS Letters; 589; 22; 11-2015; 3362-3369
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