Artículo
The regulatory role of B cells in autoimmunity, infections and cancer: Perspectives beyond IL10 production
Gorosito Serran, Melisa
; Fiocca Vernengo, Facundo
; Beccaria, Cristian Gabriel
; Acosta Rodriguez, Eva Virginia
; Montes, Carolina Lucia
; Gruppi, Adriana
Fecha de publicación:
11/2015
Editorial:
Elsevier Science
Revista:
FEBS Letters
ISSN:
0014-5793
e-ISSN:
1873-3468
Idioma:
Inglés
Tipo de recurso:
Artículo publicado
Clasificación temática:
Resumen
The term regulatory B cells (B regs) is ascribed to a heterogeneous population of B cells with the function of suppressing inflammatory responses. They have been described mainly during the last decade in the context of different immune-mediated diseases. Most of the work on B regs has been focused on IL-10-producing B cells. However, B cells can exert regulatory functions independently of IL-10 production. Here we discuss the phenotypes, development and effector mechanisms of B regs and advances in their role in autoimmunity, infections and cancer.
Palabras clave:
B Cell
,
Autoimmunity
,
Regulation
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Articulos(CIBICI)
Articulos de CENTRO DE INV.EN BIOQUI.CLINICA E INMUNOLOGIA
Articulos de CENTRO DE INV.EN BIOQUI.CLINICA E INMUNOLOGIA
Citación
Gorosito Serran, Melisa; Fiocca Vernengo, Facundo; Beccaria, Cristian Gabriel; Acosta Rodriguez, Eva Virginia; Montes, Carolina Lucia; et al.; The regulatory role of B cells in autoimmunity, infections and cancer: Perspectives beyond IL10 production; Elsevier Science; FEBS Letters; 589; 22; 11-2015; 3362-3369
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