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dc.contributor.author
Aquino, Jorge Benjamin
dc.date.available
2018-05-11T15:08:46Z
dc.date.issued
2017-03
dc.identifier.citation
Aquino, Jorge Benjamin; Uncovering the in vivo source of adult neural crest stem cells; Mary Ann Liebert; Stem Cells And Development; 26; 5; 3-2017; 303-313
dc.identifier.issn
1547-3287
dc.identifier.uri
http://hdl.handle.net/11336/44911
dc.description.abstract
Some late embryonic and adult postmigratory neural crest-derived cells (NCDCs) from diverse tissues were shown to grow as multipotent neurospheres. Neural crest stem cells (NCSCs) contained in these spheres, were found to give rise not only to neuroectodermal derivatives but also to some of the progeny of the other embryonic germ layers. In this review, evidences regarding the in vivo properties of NCDCs contributing to NCSCs are discussed. Even though in many cases the final prove for the phenotype identity of in vivo cells generating NCSCs is lacking, some evidences suggest that such postmigratory NCDCs would differ from neural crest cells (NCCs). The streamline of this review follows a historical perspective which helps understanding the advancements in knowledge of this field of research and highlighting its importance, in an appropriate context. Finally, the potential for regenerative medicine purpose of NCDCs, and more specifically of tissues which can be a source of peripheral glia progenitors in the adult, is underlined.
dc.format
application/pdf
dc.language.iso
eng
dc.publisher
Mary Ann Liebert
dc.rights
info:eu-repo/semantics/openAccess
dc.rights.uri
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
dc.subject
Neural Crest
dc.subject
Schwann Cell Precursors
dc.subject
Differentiation
dc.subject
In Vivo
dc.subject.classification
Otras Ciencias Biológicas
dc.subject.classification
Ciencias Biológicas
dc.subject.classification
CIENCIAS NATURALES Y EXACTAS
dc.title
Uncovering the in vivo source of adult neural crest stem cells
dc.type
info:eu-repo/semantics/article
dc.type
info:ar-repo/semantics/artículo
dc.type
info:eu-repo/semantics/publishedVersion
dc.date.updated
2018-03-27T15:14:58Z
dc.journal.volume
26
dc.journal.number
5
dc.journal.pagination
303-313
dc.journal.pais
Estados Unidos
dc.journal.ciudad
Nueva York
dc.description.fil
Fil: Aquino, Jorge Benjamin. Universidad Austral. Facultad de Ciencias Biomédicas. Instituto de Investigaciones en Medicina Traslacional. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Parque Centenario. Instituto de Investigaciones en Medicina Traslacional; Argentina
dc.journal.title
Stem Cells And Development
dc.relation.alternativeid
info:eu-repo/semantics/altIdentifier/url/http://online.liebertpub.com/doi/10.1089/scd.2016.0297
dc.relation.alternativeid
info:eu-repo/semantics/altIdentifier/doi/http://dx.doi.org/10.1089/scd.2016.0297
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