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dc.contributor.author
Sanchez, Leandro Arturo
dc.contributor.author
Gomez, Fiorella Fatima
dc.contributor.author
Delgado, Osvaldo Daniel
dc.date.available
2018-04-24T20:54:22Z
dc.date.issued
2008-11
dc.identifier.citation
Sanchez, Leandro Arturo; Gomez, Fiorella Fatima; Delgado, Osvaldo Daniel; Cold-adapted microorganisms as a source of new antimicrobials; Springer Tokyo; Extremophiles; 13; 1; 11-2008; 111-120
dc.identifier.issn
1431-0651
dc.identifier.uri
http://hdl.handle.net/11336/43382
dc.description.abstract
Thirty out of 8,000 different colony morphotypes isolated from soil samples of Isla de los Estados were selected based on their ability to produce antimicrobials. The significant influence of culture media and incubation temperature on antimicrobial production was proved, being LB medium and 8C the conditions of choice. Most of the psychrotolerant isolates were phylogenetically related to Serratia proteamaculans (96.4?97.9%) while the psychrophilic isolated 8H1 was closely related to Pseudomonas sp. (90?94% similarity). Produced antimicrobials showed a promising wide spectrum of activity both against grampositive and gram-negative pathogenic bacteria. They were suspected to be microcin-like compounds (Mw\2,000 Da) and showed a marked tolerance to heat (1 h in boiling water bath) and pH-treatments (1?12). Antimicrobial compounds also showed to partially keep their activity even after overnight freezing at -20 and -80C and displayed a negative net charge at pH 8.0, a common feature of class II microcins.
dc.format
application/pdf
dc.language.iso
eng
dc.publisher
Springer Tokyo
dc.rights
info:eu-repo/semantics/openAccess
dc.rights.uri
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
dc.subject
Psychrophiles
dc.subject
Psychrotolerant
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Bacteriocins
dc.subject
Microcins
dc.subject
Isla de Los Estados
dc.subject.classification
Biología Celular, Microbiología
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Ciencias Biológicas
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CIENCIAS NATURALES Y EXACTAS
dc.title
Cold-adapted microorganisms as a source of new antimicrobials
dc.type
info:eu-repo/semantics/article
dc.type
info:ar-repo/semantics/artículo
dc.type
info:eu-repo/semantics/publishedVersion
dc.date.updated
2018-04-16T13:29:42Z
dc.journal.volume
13
dc.journal.number
1
dc.journal.pagination
111-120
dc.journal.pais
Japón
dc.journal.ciudad
Tokyo
dc.description.fil
Fil: Sanchez, Leandro Arturo. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Tucumán. Planta Piloto de Procesos Industriales Microbiológicos; Argentina
dc.description.fil
Fil: Gomez, Fiorella Fatima. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Tucumán. Planta Piloto de Procesos Industriales Microbiológicos; Argentina
dc.description.fil
Fil: Delgado, Osvaldo Daniel. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Tucumán. Planta Piloto de Procesos Industriales Microbiológicos; Argentina
dc.journal.title
Extremophiles
dc.relation.alternativeid
info:eu-repo/semantics/altIdentifier/doi/https://dx.doi.org/10.1007/s00792-008-0203-5
dc.relation.alternativeid
info:eu-repo/semantics/altIdentifier/url/https://link.springer.com/article/10.1007%2Fs00792-008-0203-5
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