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dc.contributor.author
Nina, N.  
dc.contributor.author
Lima, Beatriz Viviana  
dc.contributor.author
Feresin, Gabriela Egly  
dc.contributor.author
Giménez, A.  
dc.contributor.author
Capusiri, E. S.  
dc.contributor.author
Schmeda Hirschmann, G.  
dc.date.available
2018-04-20T17:57:16Z  
dc.date.issued
2016-01  
dc.identifier.citation
Nina, N.; Lima, Beatriz Viviana; Feresin, Gabriela Egly; Giménez, A.; Capusiri, E. S.; et al.; Antibacterial and Leishmanicidal Activity of Bolivian Propolis; Wiley Blackwell Publishing, Inc; Letters in Applied Microbiology; 62; 3; 1-2016; 290-296  
dc.identifier.issn
0266-8254  
dc.identifier.uri
http://hdl.handle.net/11336/42873  
dc.description.abstract
The antimicrobial activity of Bolivian propolis was assessed for the first time on a panel of bacteria and two endemic parasitic protozoa. Ten samples of Bolivian propolis and their main constituents were tested using the micro-broth dilution method against 11 bacterial pathogenic strains as well as against promastigotes of Leishmania amazonensis and L. braziliensis using the XTT-based colorimetric method. The methanolic extracts showed antibacterial effect ranging from inactive (MICs >1000 μg ml(-1) ) to low (MICs 250-1000 μg ml(-1) ), moderate (62∙5-125 μg ml(-1) ) and high antibacterial activity (MIC 31.2 μg ml(-1) ), according to the collection place and chemical composition. The most active samples towards Leishmania species were from Cochabamba and Tarija, with IC50 values of 12∙1 and 7∙8, 8∙0 and 10∙9 μg ml(-1) against L. amazonensis and L. brasiliensis, respectively. The results show that the best antibacterial and antiprotozoal effect was observed for some phenolic rich propolis.  
dc.format
application/pdf  
dc.language.iso
eng  
dc.publisher
Wiley Blackwell Publishing, Inc  
dc.rights
info:eu-repo/semantics/openAccess  
dc.rights.uri
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/  
dc.subject
Bolivia  
dc.subject
Propolis  
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Antibacterial Activity  
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Bacteria  
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Disinfectant  
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Leishmanicidal Activity  
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Phenolics  
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Triterpenes  
dc.subject.classification
Otras Ciencias Químicas  
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Ciencias Químicas  
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CIENCIAS NATURALES Y EXACTAS  
dc.title
Antibacterial and Leishmanicidal Activity of Bolivian Propolis  
dc.type
info:eu-repo/semantics/article  
dc.type
info:ar-repo/semantics/artículo  
dc.type
info:eu-repo/semantics/publishedVersion  
dc.date.updated
2018-04-18T14:53:31Z  
dc.journal.volume
62  
dc.journal.number
3  
dc.journal.pagination
290-296  
dc.journal.pais
Reino Unido  
dc.journal.ciudad
Londres  
dc.description.fil
Fil: Nina, N.. Universidad de Talca; Chile  
dc.description.fil
Fil: Lima, Beatriz Viviana. Universidad Nacional de San Juan. Facultad de Ingeniería. Instituto de Biotecnología; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina  
dc.description.fil
Fil: Feresin, Gabriela Egly. Universidad Nacional de San Juan. Facultad de Ingeniería. Instituto de Biotecnología; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina  
dc.description.fil
Fil: Giménez, A.. Universidad Mayor de San Andrés; Bolivia  
dc.description.fil
Fil: Capusiri, E. S.. Universidad Mayor de San Andrés; Bolivia  
dc.description.fil
Fil: Schmeda Hirschmann, G.. Universidad de Talca; Chile  
dc.journal.title
Letters in Applied Microbiology  
dc.relation.alternativeid
info:eu-repo/semantics/altIdentifier/doi/http://dx.doi.org/10.1111/lam.12543  
dc.relation.alternativeid
info:eu-repo/semantics/altIdentifier/url/https://onlinelibrary.wiley.com/doi/abs/10.1111/lam.12543