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dc.contributor.author Stella, Flavia
dc.contributor.author Pedrazzini, Estela Marta
dc.contributor.author Agazzoni, Mara
dc.contributor.author Ballester, Oscar
dc.contributor.author Slavutsky, Irma Rosa
dc.date.available 2018-04-19T20:01:33Z
dc.date.issued 2015-10
dc.identifier.citation Stella, Flavia; Pedrazzini, Estela Marta; Agazzoni, Mara; Ballester, Oscar; Slavutsky, Irma Rosa; Cytogenetic alterations in multiple myeloma: prognostic significance and the choice of frontline therapy; Taylor; Cancer Investigation; 33; 10; 10-2015; 496-504
dc.identifier.issn 0735-7907
dc.identifier.uri http://hdl.handle.net/11336/42743
dc.description.abstract Multiple myeloma tumor cells demonstrate multiple and often complex genetic lesions as evaluated by standard cytogenetic/FISH studies. Over the past decade, specific abnormalities have been associated with standard or high-risk clinical behavior and they have become strong prognostic indicators. Further, as evidenced by recent randomized clinical trials, the choice of front-line therapy (transplant vs. no transplant, inclusion of novel drugs such as bortezomib, thalidomide, and lenalidomide) may be able to overcome the adverse effect of high-risk genetic lesions.
dc.format application/pdf
dc.language.iso eng
dc.publisher Taylor
dc.rights info:eu-repo/semantics/restrictedAccess
dc.rights.uri https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
dc.subject CYTOGENETICS
dc.subject FISH
dc.subject MULTIPLE MYELOMA
dc.subject THERAPY
dc.subject.classification Inmunología
dc.subject.classification Medicina Básica
dc.subject.classification CIENCIAS MÉDICAS Y DE LA SALUD
dc.subject.classification Genética Humana
dc.subject.classification Medicina Básica
dc.subject.classification CIENCIAS MÉDICAS Y DE LA SALUD
dc.title Cytogenetic alterations in multiple myeloma: prognostic significance and the choice of frontline therapy
dc.type info:eu-repo/semantics/article
dc.type info:ar-repo/semantics/artículo
dc.type info:eu-repo/semantics/publishedVersion
dc.date.updated 2018-04-09T19:05:20Z
dc.identifier.eissn 1532-4192
dc.journal.volume 33
dc.journal.number 10
dc.journal.pagination 496-504
dc.journal.pais Estados Unidos
dc.journal.ciudad Abingdon
dc.description.fil Fil: Stella, Flavia. Consejo Nacional de Investigaciones Científicas y Técnicas. Instituto de Medicina Experimental. Academia Nacional de Medicina de Buenos Aires. Instituto de Medicina Experimental; Argentina
dc.description.fil Fil: Pedrazzini, Estela Marta. Consejo Nacional de Investigaciones Científicas y Técnicas. Instituto de Medicina Experimental. Academia Nacional de Medicina de Buenos Aires. Instituto de Medicina Experimental; Argentina
dc.description.fil Fil: Agazzoni, Mara. Consejo Nacional de Investigaciones Científicas y Técnicas. Instituto de Medicina Experimental. Academia Nacional de Medicina de Buenos Aires. Instituto de Medicina Experimental; Argentina
dc.description.fil Fil: Ballester, Oscar. Consejo Nacional de Investigaciones Científicas y Técnicas. Instituto de Medicina Experimental. Academia Nacional de Medicina de Buenos Aires. Instituto de Medicina Experimental; Argentina
dc.description.fil Fil: Slavutsky, Irma Rosa. Consejo Nacional de Investigaciones Científicas y Técnicas. Instituto de Medicina Experimental. Academia Nacional de Medicina de Buenos Aires. Instituto de Medicina Experimental; Argentina
dc.journal.title Cancer Investigation
dc.relation.alternativeid info:eu-repo/semantics/altIdentifier/url/https://www.tandfonline.com/doi/abs/10.3109/07357907.2015.1080833?journalCode=icnv20
dc.relation.alternativeid info:eu-repo/semantics/altIdentifier/doi/http://dx.doi.org/10.3109/07357907.2015.1080833
dc.relation.alternativeid info:eu-repo/semantics/altIdentifier/pmid/26506456
dc.conicet.fuente individual


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info:eu-repo/semantics/restrictedAccess Excepto donde se diga explícitamente, este item se publica bajo la siguiente descripción: Creative Commons Attribution-NonCommercial-ShareAlike 2.5 Unported (CC BY-NC-SA 2.5)