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dc.contributor.author
Angiolella, Letizia
dc.contributor.author
Leone, Claudia
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Rojas, Florencia Dinorah
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Mussin, Javier Esteban
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Sosa, Maria de Los Angeles
dc.contributor.author
Giusiano, Gustavo Emilio
dc.date.available
2018-04-16T13:40:48Z
dc.date.issued
2018-01
dc.identifier.citation
Angiolella, Letizia; Leone, Claudia; Rojas, Florencia Dinorah; Mussin, Javier Esteban; Sosa, Maria de Los Angeles; et al.; Biofilm, adherence, and hydrophobicity as virulence factors in Malassezia furfur; Taylor & Francis Ltd; Medical Mycology; 56; 1; 1-2018; 110-116
dc.identifier.issn
1369-3786
dc.identifier.uri
http://hdl.handle.net/11336/42092
dc.description.abstract
Malassezia species are natural inhabitants of the healthy skin. However, under certain conditions, they may cause or exacerbate several skin diseases. The ability of this fungus to colonize or infect is determined by complex interactions between the fungal cell and its virulence factors. This study aims to evaluate “in vitro” the hydrophobicity levels, the adherence on a plastic surface and the biofilm formation of 16 clinical isolates of Malassezia furfur. Cellular surface hydrophobicity (CSH) levels were determined by two-phase system. The biofilm formation was determined by tetrazolium salt (XTT) reduction assay and by Scanning Electron Microscopy (SEM). Results showed many isolates were hydrophobic, adherent, and producers of biofilm on abiotic surfaces with different capacity. SEM observations confirmed an abundant extracellular matrix after 48 h of biofilm formation. About 63% of strains with high production of biofilm showed medium to high percentage of hydrophobicity and/or adherence. In addition, it has been demonstrated a correlation between hydrophobicity, adherence, and biofilm formation in about 60% of strains examined. These important virulence factors could be responsible of this yeast changing from a commensal to a pathogenic status.
dc.format
application/pdf
dc.language.iso
eng
dc.publisher
Taylor & Francis Ltd
dc.rights
info:eu-repo/semantics/openAccess
dc.rights.uri
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
dc.subject
Malassezia
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Hydrophobicity
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Scanning Electron Microscopy
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Adherence
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Otras Ciencias Biológicas
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Ciencias Biológicas
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CIENCIAS NATURALES Y EXACTAS
dc.title
Biofilm, adherence, and hydrophobicity as virulence factors in Malassezia furfur
dc.type
info:eu-repo/semantics/article
dc.type
info:ar-repo/semantics/artículo
dc.type
info:eu-repo/semantics/publishedVersion
dc.date.updated
2018-04-04T14:35:28Z
dc.identifier.eissn
1460-2709
dc.journal.volume
56
dc.journal.number
1
dc.journal.pagination
110-116
dc.journal.pais
Reino Unido
dc.journal.ciudad
Londres
dc.description.fil
Fil: Angiolella, Letizia. Instituto de Investigaciones Universitarias Roma la Sapienza; Italia
dc.description.fil
Fil: Leone, Claudia. Instituto de Investigaciones Universitarias Roma la Sapienza; Italia
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Fil: Rojas, Florencia Dinorah. Universidad Nacional del Nordeste. Instituto de Medicina Regional; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina
dc.description.fil
Fil: Mussin, Javier Esteban. Universidad Nacional del Nordeste. Instituto de Medicina Regional; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina
dc.description.fil
Fil: Sosa, Maria de Los Angeles. Universidad Nacional del Nordeste. Instituto de Medicina Regional; Argentina
dc.description.fil
Fil: Giusiano, Gustavo Emilio. Universidad Nacional del Nordeste. Instituto de Medicina Regional; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina
dc.journal.title
Medical Mycology
dc.relation.alternativeid
info:eu-repo/semantics/altIdentifier/url/https://academic.oup.com/mmy/article-lookup/doi/10.1093/mmy/myx014
dc.relation.alternativeid
info:eu-repo/semantics/altIdentifier/doi/http://dx.doi.org/10.1093/mmy/myx014
dc.relation.alternativeid
info:eu-repo/semantics/altIdentifier/url/https://academic.oup.com/mmy/issue/56/1
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