Mostrar el registro sencillo del ítem
dc.contributor.author
Lassalle, Verónica Leticia
dc.contributor.author
Ferreira, María Luján
dc.date.available
2018-04-13T14:25:19Z
dc.date.issued
2008-10
dc.identifier.citation
Lassalle, Verónica Leticia; Ferreira, María Luján; Lipase-catalyzed synthesis of polylactic acid: an overview of the experimental aspects; John Wiley & Sons Ltd; Journal of Chemical Technology and Biotechnology; 83; 11; 10-2008; 1493-1502
dc.identifier.issn
0268-2575
dc.identifier.uri
http://hdl.handle.net/11336/41971
dc.description.abstract
BACKGROUND: Enzymes have received increasing attention as biocatalysts. The poly(lactic) acid (PLA) has been widely employed in biomedical applications and PLA synthesis by a ‘green route’ is of particular interest. Here the aim is to prepare PLA using lipases, focusing on optimization of the procedure. The effects of the type and concentration of lipase, type of reaction, solvent, and time on the recovery of solid polyester, conversion rate and molecular weight have been explored. Pseudomonas cepacia (PCL), Porcine pancreatic lipase (PPL) and immobilized CAL‐B were used as biocatalysts. RESULTS: CAL‐B was the most effective biocatalyst, with 60% LA conversion and 55% recovered solid polymer; PCL and PPL gave rise to poor recovery of polymer. A novel thermal treatment was successfully employed to enhance the molecular weight Mn of PLA. CONCLUSIONS: This work offers a set of optimal conditions to synthesize PLA as a function of the lipase used. Information of this nature is currently not available in the literature, thus the findings here are a valuable tool for any researcher in this topic and a state‐of‐the‐art contribution in terms of the best biocatalyst and the best conditions for PLA synthesis. Copyright © 2008 Society of Chemical Industry
dc.format
application/pdf
dc.language.iso
eng
dc.publisher
John Wiley & Sons Ltd
dc.rights
info:eu-repo/semantics/openAccess
dc.rights.uri
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
dc.subject
Biocatalysis
dc.subject
Enzymatic Polymerization
dc.subject
Polylactic Acid
dc.subject
Enzymes
dc.subject
Lipase
dc.subject
Lactic Acid
dc.subject.classification
Otras Ciencias Químicas
dc.subject.classification
Ciencias Químicas
dc.subject.classification
CIENCIAS NATURALES Y EXACTAS
dc.title
Lipase-catalyzed synthesis of polylactic acid: an overview of the experimental aspects
dc.type
info:eu-repo/semantics/article
dc.type
info:ar-repo/semantics/artículo
dc.type
info:eu-repo/semantics/publishedVersion
dc.date.updated
2018-04-05T18:20:08Z
dc.journal.volume
83
dc.journal.number
11
dc.journal.pagination
1493-1502
dc.journal.pais
Reino Unido
dc.journal.ciudad
Londres
dc.description.fil
Fil: Lassalle, Verónica Leticia. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Bahía Blanca. Instituto de Química del Sur. Universidad Nacional del Sur. Departamento de Química. Instituto de Química del Sur; Argentina
dc.description.fil
Fil: Ferreira, María Luján. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Bahía Blanca. Planta Piloto de Ingeniería Química. Universidad Nacional del Sur. Planta Piloto de Ingeniería Química; Argentina
dc.journal.title
Journal of Chemical Technology and Biotechnology
dc.relation.alternativeid
info:eu-repo/semantics/altIdentifier/doi/http://dx.doi.org/10.1002/jctb.1994
dc.relation.alternativeid
info:eu-repo/semantics/altIdentifier/url/https://onlinelibrary.wiley.com/doi/abs/10.1002/jctb.1994
Archivos asociados