Artículo
Comparative Efficacies of TAK-187, a Long-Lasting Ergosterol Biosynthesis Inhibitor, and Benznidazole in Preventing Cardiac Damage in a Murine Model of Chagas' Disease
Corrales, Milagros; Cardozo, Rubén Marino; Segura, Maria Asuncion; Urbina, Julio A.; Basombrío, Miguel Ángel Manuel
Fecha de publicación:
03/2005
Editorial:
American Society for Microbiology
Revista:
Antimicrobial Agents and Chemotherapy
ISSN:
0066-4804
Idioma:
Inglés
Tipo de recurso:
Artículo publicado
Clasificación temática:
Resumen
We carried out a comparative study of benznidazole and TAK-187, a long-lasting ergosterol biosynthesis inhibitor, with a murine model of Chagas` disease. The results indicated that TAK-187 was more effective than benznidazole in preventing Trypanosoma cruzi-induced cardiac damage in experimental animals.
Palabras clave:
Tak-187
,
Trypanosoma Cruzi
,
Benznidazole
,
Cardiac Damage
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Articulos(IPE)
Articulos de INST.DE PATOLOGIA EXPERIMENTAL
Articulos de INST.DE PATOLOGIA EXPERIMENTAL
Citación
Corrales, Milagros; Cardozo, Rubén Marino; Segura, Maria Asuncion; Urbina, Julio A.; Basombrío, Miguel Ángel Manuel; Comparative Efficacies of TAK-187, a Long-Lasting Ergosterol Biosynthesis Inhibitor, and Benznidazole in Preventing Cardiac Damage in a Murine Model of Chagas' Disease; American Society for Microbiology; Antimicrobial Agents and Chemotherapy; 49; 4; 3-2005; 1556-1560
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