Mostrar el registro sencillo del ítem
dc.contributor.author
Farré, Eva M.
dc.contributor.author
Harmer, Stacey L.
dc.contributor.author
Harmon, Frank G.
dc.contributor.author
Yanovsky, Marcelo Javier
![Se ha confirmado la validez de este valor de autoridad por un usuario](/themes/CONICETDigital/images/authority_control/invisible.gif)
dc.contributor.author
Kay, Steve A.
dc.date.available
2018-04-06T17:28:34Z
dc.date.issued
2005-01
dc.identifier.citation
Farré, Eva M.; Harmer, Stacey L.; Harmon, Frank G.; Yanovsky, Marcelo Javier; Kay, Steve A.; Overlapping and Distinct Roles of PRR7 and PRR9 in the Arabidopsis Circadian Clock; Cell Press; Current Biology; 15; 1; 1-2005; 47-54
dc.identifier.issn
0960-9822
dc.identifier.uri
http://hdl.handle.net/11336/41159
dc.description.abstract
The core mechanism of the circadian oscillators described to date rely on transcriptional negative feedback loops with a delay between the negative and the positive components [1-3]. In plants, the first suggested regulatory loop involves the transcription factors CIRCADIAN CLOCK-ASSOCIATED 1 (CCA1) and LATE ELONGATED HYPOCOTYL (LHY) and the pseudo-response regulator TIMING OF CAB EXPRESSION 1 (TOC1/PRR1)[4]. TOC1 is a member of the Arabidopsis circadian-regulated PRR gene family [5,6]. Analysis of single and double mutants in PRR7 and PRR9 indicates that these morning-expressed genes play a dual role in the circadian clock, being involved in the transmission of light signals to the clock and in the regulation of the central oscillator. Furthermore, CCA1 and LHY had a positive effect on PRR7 and PRR9 expression levels, indicating that they might form part of an additional regulatory feedback loop. We propose that the Arabidopsis circadian oscillator is composed of several interlocking positive and negative feedback loops, a feature of clock regulation that appears broadly conserved between plants, fungi, and animals.
dc.format
application/pdf
dc.language.iso
eng
dc.publisher
Cell Press
![Se ha confirmado la validez de este valor de autoridad por un usuario](/themes/CONICETDigital/images/authority_control/invisible.gif)
dc.rights
info:eu-repo/semantics/openAccess
dc.rights.uri
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
dc.subject
Circadian Clock
dc.subject.classification
Otras Ciencias Biológicas
![Se ha confirmado la validez de este valor de autoridad por un usuario](/themes/CONICETDigital/images/authority_control/invisible.gif)
dc.subject.classification
Ciencias Biológicas
![Se ha confirmado la validez de este valor de autoridad por un usuario](/themes/CONICETDigital/images/authority_control/invisible.gif)
dc.subject.classification
CIENCIAS NATURALES Y EXACTAS
![Se ha confirmado la validez de este valor de autoridad por un usuario](/themes/CONICETDigital/images/authority_control/invisible.gif)
dc.title
Overlapping and Distinct Roles of PRR7 and PRR9 in the Arabidopsis Circadian Clock
dc.type
info:eu-repo/semantics/article
dc.type
info:ar-repo/semantics/artículo
dc.type
info:eu-repo/semantics/publishedVersion
dc.date.updated
2018-04-05T19:23:02Z
dc.identifier.eissn
1879-0445
dc.journal.volume
15
dc.journal.number
1
dc.journal.pagination
47-54
dc.journal.pais
Estados Unidos
![Se ha confirmado la validez de este valor de autoridad por un usuario](/themes/CONICETDigital/images/authority_control/invisible.gif)
dc.journal.ciudad
Cambridge
dc.description.fil
Fil: Farré, Eva M.. The Scripps Research Institute; Estados Unidos
dc.description.fil
Fil: Harmer, Stacey L.. University of California; Estados Unidos
dc.description.fil
Fil: Harmon, Frank G.. The Scripps Research Institute; Estados Unidos
dc.description.fil
Fil: Yanovsky, Marcelo Javier. The Scripps Research Institute; Estados Unidos. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Parque Centenario. Instituto de Investigaciones Bioquímicas de Buenos Aires. Fundación Instituto Leloir. Instituto de Investigaciones Bioquímicas de Buenos Aires; Argentina
dc.description.fil
Fil: Kay, Steve A.. The Scripps Research Institute; Estados Unidos
dc.journal.title
Current Biology
![Se ha confirmado la validez de este valor de autoridad por un usuario](/themes/CONICETDigital/images/authority_control/invisible.gif)
dc.relation.alternativeid
info:eu-repo/semantics/altIdentifier/url/http://www.cell.com/current-biology/fulltext/S0960-9822(04)01024-3
dc.relation.alternativeid
info:eu-repo/semantics/altIdentifier/doi/http://dx.doi.org/10.1016/j.cub.2004.12.067
Archivos asociados