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dc.contributor.author
Rybkin, IIya
dc.contributor.author
Gerometta, Rosana María del Rosario
dc.contributor.author
Fridman, Gabrielle
dc.contributor.author
Candia, Oscar
dc.contributor.author
Danias, John
dc.date.available
2018-03-23T15:20:45Z
dc.date.issued
2017-05
dc.identifier.citation
Rybkin, IIya; Gerometta, Rosana María del Rosario; Fridman, Gabrielle; Candia, Oscar; Danias, John; Model systems for the study of steroid-induced IOP elevation; Academic Press Ltd - Elsevier Science Ltd; Experimental Eye Research; 158; 5-2017; 51-58
dc.identifier.issn
0014-4835
dc.identifier.uri
http://hdl.handle.net/11336/39762
dc.description.abstract
Steroid-induced IOP elevation affects a significant number of patients. It results from a decrease in outflow facility of the aqueous humor. To understand the pathophysiology of this condition a number of model systems have been created. These include ex-vivo cell and organ cultures as well as in-vivo animal models in organisms ranging from rodents to primates. These model systems can be used to investigate specific aspects of steroid-induced IOP elevation. This brief review summarizes the strengths and limitations of the various model systems and provides examples of where these systems have been successfully used to advance our understanding of steroid-induced IOP elevation.
dc.format
application/pdf
dc.language.iso
eng
dc.publisher
Academic Press Ltd - Elsevier Science Ltd
dc.rights
info:eu-repo/semantics/openAccess
dc.rights.uri
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
dc.subject
GLAUCOMA
dc.subject
INTRAOCULAR PRESSURE
dc.subject
MODEL
dc.subject
STEROIDS
dc.subject.classification
Medicina Critica y de Emergencia
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Medicina Clínica
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CIENCIAS MÉDICAS Y DE LA SALUD
dc.title
Model systems for the study of steroid-induced IOP elevation
dc.type
info:eu-repo/semantics/article
dc.type
info:ar-repo/semantics/artículo
dc.type
info:eu-repo/semantics/publishedVersion
dc.date.updated
2018-03-20T13:14:57Z
dc.journal.volume
158
dc.journal.pagination
51-58
dc.journal.pais
Reino Unido
dc.journal.ciudad
Manchester
dc.description.fil
Fil: Rybkin, IIya. SUNY Downstate; Estados Unidos
dc.description.fil
Fil: Gerometta, Rosana María del Rosario. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina. Universidad Nacional del Comahue. Facultad de Medicina; Argentina. Icahn School of Medicine at Mount Sinai; Estados Unidos
dc.description.fil
Fil: Fridman, Gabrielle. SUNY Downstate; Estados Unidos
dc.description.fil
Fil: Candia, Oscar. Icahn School of Medicine at Mount Sinai; Estados Unidos
dc.description.fil
Fil: Danias, John. SUNY Downstate; Estados Unidos
dc.journal.title
Experimental Eye Research
dc.relation.alternativeid
info:eu-repo/semantics/altIdentifier/doi/http://dx.doi.org/10.1016/j.exer.2016.07.013
dc.relation.alternativeid
info:eu-repo/semantics/altIdentifier/url/https://www.sciencedirect.com/science/article/pii/S0014483516301944
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