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dc.contributor.author
Díaz, Jimena Estela  
dc.contributor.author
Mollo, María Cruz  
dc.contributor.author
Orelli, Liliana Raquel  
dc.date.available
2018-03-20T17:58:51Z  
dc.date.issued
2016-09  
dc.identifier.citation
Díaz, Jimena Estela; Mollo, María Cruz; Orelli, Liliana Raquel; Microwave-assisted cyclizations promoted by polyphosphoric acid esters: A general method for 1-aryl-2-iminoazacycloalkanes; Beilstein-Institut; Beilstein Journal Of Organic Chemistry; 12; 9-2016; 2026-2031  
dc.identifier.issn
1860-5397  
dc.identifier.uri
http://hdl.handle.net/11336/39371  
dc.description.abstract
The first general procedure for the synthesis of 5 to 7-membered 1-aryl-2-iminoazacycloalkanes is presented, by microwave-assisted ring closure of ω-arylaminonitriles promoted by polyphosphoric acid (PPA) esters. 1-Aryl-2-iminopyrrolidines were easily prepared from the acyclic precursors employing a chloroformic solution of ethyl polyphosphate (PPE). The use of trimethylsilyl polyphosphate (PPSE) in solvent-free conditions allowed for the synthesis of 1-aryl-2-iminopiperidines and hitherto unreported 1-aryl-2-iminoazepanes. The cyclization reaction involves good to high yields and short reaction times, and represents a novel application of PPA esters in heterocyclic synthesis.  
dc.format
application/pdf  
dc.language.iso
eng  
dc.publisher
Beilstein-Institut  
dc.rights
info:eu-repo/semantics/openAccess  
dc.rights.uri
https://creativecommons.org/licenses/by/2.5/ar/  
dc.subject
Cyclic Amidines  
dc.subject
Medium Size Heterocycles  
dc.subject
Microwaves  
dc.subject
Ppe  
dc.subject
Ppse  
dc.subject.classification
Otras Ciencias Químicas  
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Ciencias Químicas  
dc.subject.classification
CIENCIAS NATURALES Y EXACTAS  
dc.title
Microwave-assisted cyclizations promoted by polyphosphoric acid esters: A general method for 1-aryl-2-iminoazacycloalkanes  
dc.type
info:eu-repo/semantics/article  
dc.type
info:ar-repo/semantics/artículo  
dc.type
info:eu-repo/semantics/publishedVersion  
dc.date.updated
2018-03-20T14:35:59Z  
dc.journal.volume
12  
dc.journal.pagination
2026-2031  
dc.journal.pais
Alemania  
dc.description.fil
Fil: Díaz, Jimena Estela. Universidad de Buenos Aires. Facultad de Farmacia y Bioquímica. Departamento de Química Orgánica; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina  
dc.description.fil
Fil: Mollo, María Cruz. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina. Universidad de Buenos Aires. Facultad de Farmacia y Bioquímica. Departamento de Química Orgánica; Argentina  
dc.description.fil
Fil: Orelli, Liliana Raquel. Universidad de Buenos Aires. Facultad de Farmacia y Bioquímica. Departamento de Química Orgánica; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina  
dc.journal.title
Beilstein Journal Of Organic Chemistry  
dc.relation.alternativeid
info:eu-repo/semantics/altIdentifier/doi/http://dx.doi.org/10.3762/bjoc.12.190  
dc.relation.alternativeid
info:eu-repo/semantics/altIdentifier/url/https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5082496/  
dc.relation.alternativeid
info:eu-repo/semantics/altIdentifier/url/https://www.beilstein-journals.org/bjoc/articles/12/190  

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