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dc.contributor.author
Yanzón de La Torre, Andrés
dc.contributor.author
Oliva, Nicolás
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Echevarrieta, Paula L.
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Pérez, Bibiana G.
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Caporusso, Gabriela B.
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Titaro, Anabella J.
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Todaro Kicyla, Alejandro
dc.contributor.author
Cuatz, Mariana
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Locatelli, Mariana
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Nelson, Lucila M.
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Mac Mullen, Mercedes
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Baldessarini, Ross J.
dc.contributor.author
Daray, Federico Manuel
dc.date.available
2018-03-15T20:12:04Z
dc.date.issued
2016-06
dc.identifier.citation
Yanzón de La Torre, Andrés; Oliva, Nicolás; Echevarrieta, Paula L.; Pérez, Bibiana G.; Caporusso, Gabriela B.; et al.; Major depression in hospitalized Argentine general medical patients: Prevalence and risk factors; Elsevier Science; Journal of Affective Disorders; 197; 6-2016; 36-42
dc.identifier.issn
0165-0327
dc.identifier.uri
http://hdl.handle.net/11336/39010
dc.description.abstract
Background: Depression is not uncommon among medically hospitalized patients, though reported prevalence has varied widely, often in samples involving elderly patients with particular illnesses. Accordingly, we evaluated risk of major depression in three metropolitan general hospitals in Buenos Aires, in subjects with a range of medical disorders and ages, comparing several standard screening methods to expert clinical examinations. Methods: Consecutively hospitalized general medical patients were evaluated over a six-months. Excluded were subjects under age 18 and those unable to participate in assessments because of illness, medication, sensory or speech impairment, or lack of language fluency, or scored <25 on the Mini Mental State Examination (MMSE). Consenting participants were examined for DSM-IV-TR major depression by psychiatrists guided by MINI examinations, compared with other standard screening methods. Risk factors were assessed by preliminary bivariate analyses followed by multivariate logistic regression modeling. Results: Overall prevalence of major depression in 257 subjects was 27% by psychiatric examination. The rate was most similar (25%) with the Hospital Anxiety & Depression Scale (HADS), and much higher with the Beck Depression Inventory-II (BDI, 44%) and Patient Health Questionnaire (PHQ, 56%). Factors associated independently with depression by multivariate modeling included: Prior psychotropic-drug treatment, female sex, more children, and heavy smoking. Depression was associated most with neoplastic, urological, and infectious disorders, least with pulmonary, neurological, and hematologic conditions. Limitations: Modest numbers limited power to test for associations of depression with specific medical conditions. Conclusions: Major depression was identified in over one-quarter of Argentine, general medical inpatients, with marked differences among screening methods. Several risk factors were identified. The findings encourage assertive identification of depression in hospitalized medical patients using valid, reliable, and cost-effective means of improving their care.
dc.format
application/pdf
dc.language.iso
eng
dc.publisher
Elsevier Science
dc.rights
info:eu-repo/semantics/restrictedAccess
dc.rights.uri
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
dc.subject
Depression
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General Hospital
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Prevalence
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Risk Factors
dc.subject.classification
Medicina Critica y de Emergencia
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Medicina Clínica
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CIENCIAS MÉDICAS Y DE LA SALUD
dc.title
Major depression in hospitalized Argentine general medical patients: Prevalence and risk factors
dc.type
info:eu-repo/semantics/article
dc.type
info:ar-repo/semantics/artículo
dc.type
info:eu-repo/semantics/publishedVersion
dc.date.updated
2018-03-15T14:04:00Z
dc.journal.volume
197
dc.journal.pagination
36-42
dc.journal.pais
Países Bajos
dc.journal.ciudad
Amsterdam
dc.description.fil
Fil: Yanzón de La Torre, Andrés. Provincia de Buenos Aires. Ministerio de Salud. Hospital Interzonal de Agudos ; Argentina
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Fil: Oliva, Nicolás. Gobierno de la Ciudad de Buenos Aires. Hospital General de Agudos Bernardino Rivadavia; Argentina
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Fil: Echevarrieta, Paula L.. Provincia de Buenos Aires. Ministerio de Salud. Hospital Municipal Bernardo A. Houssay; Argentina
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Fil: Pérez, Bibiana G.. Provincia de Buenos Aires. Ministerio de Salud. Hospital Municipal Bernardo A. Houssay; Argentina
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Fil: Caporusso, Gabriela B.. Provincia de Buenos Aires. Ministerio de Salud. Hospital Interzonal de Agudos ; Argentina
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Fil: Titaro, Anabella J.. Provincia de Buenos Aires. Ministerio de Salud. Hospital Interzonal de Agudos ; Argentina
dc.description.fil
Fil: Todaro Kicyla, Alejandro. Provincia de Buenos Aires. Ministerio de Salud. Hospital Interzonal de Agudos ; Argentina
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Fil: Cuatz, Mariana. Universidad de Buenos Aires. Facultad de Medicina; Argentina
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Fil: Locatelli, Mariana. Gobierno de la Ciudad de Buenos Aires. Hospital General de Agudos Bernardino Rivadavia; Argentina
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Fil: Nelson, Lucila M.. Gobierno de la Ciudad de Buenos Aires. Hospital General de Agudos Bernardino Rivadavia; Argentina
dc.description.fil
Fil: Mac Mullen, Mercedes. Universidad de Buenos Aires. Facultad de Medicina; Argentina
dc.description.fil
Fil: Baldessarini, Ross J.. Harvard Medical School; Estados Unidos
dc.description.fil
Fil: Daray, Federico Manuel. Universidad de Buenos Aires. Facultad de Medicina; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina
dc.journal.title
Journal of Affective Disorders
dc.relation.alternativeid
info:eu-repo/semantics/altIdentifier/doi/http://dx.doi.org/10.1016/j.jad.2016.02.066
dc.relation.alternativeid
info:eu-repo/semantics/altIdentifier/url/https://www.sciencedirect.com/science/article/pii/S0165032715312726


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