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dc.contributor.author
Ratti, Pietro Luca
dc.contributor.author
Negre Pages, Laurence
dc.contributor.author
Pérez Lloret, Santiago
dc.contributor.author
Manni, Raffaele
dc.contributor.author
Damier, Philippe
dc.contributor.author
Tison, Francois
dc.contributor.author
Destée, Alain
dc.contributor.author
Rascol, Olivier
dc.date.available
2018-03-15T19:03:38Z
dc.date.issued
2015-11
dc.identifier.citation
Ratti, Pietro Luca; Negre Pages, Laurence; Pérez Lloret, Santiago; Manni, Raffaele; Damier, Philippe; et al.; Subjective sleep dysfunction and insomnia symptoms in Parkinson's disease: Insights from a cross-sectional evaluation of the French CoPark cohort; Elsevier; Parkinsonism & Related Disorders; 21; 11; 11-2015; 1323-1329
dc.identifier.issn
1353-8020
dc.identifier.uri
http://hdl.handle.net/11336/38986
dc.description.abstract
Introduction: Twenty-seven to 80% of patients with Parkinson's Disease (PD) complain of subjective sleep dysfunction and insomnia symptoms. Our aim is to describe the prevalence and features of subjective sleep dysfunction and insomnia symptoms in patients with PD compared to other patients. Methods: Cross-sectional analysis of 636 adult PD patients compared to 143 age and sex-matched non-PD control patients consulting their general practitioners. Insomnia symptoms and other sleep features were assessed by the Pittsburgh Sleep Quality Index (PSQI), a global score > 5 defining impaired sleep. The Chi-square test or the Student's t-test were used to assess the potential clinical and demographic differences between groups and between PD patients with vs. without sleep dysfunction. Logistic regression analysis was employed to test multivariate effects. Results: Sleep dysfunction and insomnia symptoms were more frequent in PD patients compared to control patients (63 vs. 45%, p = 0.001). Female gender, PD duration, presence of depression and anxiety were associated with the presence of insomnia in PD. Subjective sleep efficiency, habitual sleep quality, sleep disturbance and daytime dysfunction, but not sleep latency, were reduced in PD patients compared to controls. Conclusions: The prevalence of sleep dysfunction is higher in PD than in other general medical conditions. Insomnia in PD seems to affect sleep maintenance and consolidation, but not sleep onset.
dc.format
application/pdf
dc.language.iso
eng
dc.publisher
Elsevier
dc.rights
info:eu-repo/semantics/openAccess
dc.rights.uri
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
dc.subject
Epidemiology
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Insomnia
dc.subject
Parkinson'S Disease
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Sleep Dysfunction
dc.subject.classification
Medicina Critica y de Emergencia
dc.subject.classification
Medicina Clínica
dc.subject.classification
CIENCIAS MÉDICAS Y DE LA SALUD
dc.title
Subjective sleep dysfunction and insomnia symptoms in Parkinson's disease: Insights from a cross-sectional evaluation of the French CoPark cohort
dc.type
info:eu-repo/semantics/article
dc.type
info:ar-repo/semantics/artículo
dc.type
info:eu-repo/semantics/publishedVersion
dc.date.updated
2018-03-14T17:03:55Z
dc.journal.volume
21
dc.journal.number
11
dc.journal.pagination
1323-1329
dc.journal.pais
Países Bajos
dc.journal.ciudad
Amsterdam
dc.description.fil
Fil: Ratti, Pietro Luca. Université Paul Sabatier; Francia. Inserm; Francia. Sleep and Epilepsy Center; Suiza. Toulouse University Hospital; Francia
dc.description.fil
Fil: Negre Pages, Laurence. Toulouse University Hospital; Francia. Université Paul Sabatier; Francia
dc.description.fil
Fil: Pérez Lloret, Santiago. Toulouse University Hospital; Francia. Université Paul Sabatier; Francia. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Houssay. Instituto de Investigaciones Cardiológicas. Universidad de Buenos Aires. Facultad de Medicina. Instituto de Investigaciones Cardiológicas; Argentina
dc.description.fil
Fil: Manni, Raffaele. Istituto di Ricovero e Cura a Carattere Scientifico. Istituto Neurologico Nazionale a Carattere Scientifico; Italia
dc.description.fil
Fil: Damier, Philippe. Universite de Nantes; Francia
dc.description.fil
Fil: Tison, Francois. Universite de Bordeaux; Francia
dc.description.fil
Fil: Destée, Alain. Centre Hospitalier Universitaire de Lille. Pôle de Neurologie. Service de Neurologie et pathologie du mouvement; Francia
dc.description.fil
Fil: Rascol, Olivier. Toulouse University Hospital; Francia. Inserm; Francia. Toulouse University Hospital; Francia. Université Paul Sabatier; Francia
dc.journal.title
Parkinsonism & Related Disorders
dc.relation.alternativeid
info:eu-repo/semantics/altIdentifier/url/https://www.sciencedirect.com/science/article/pii/S1353802015004009
dc.relation.alternativeid
info:eu-repo/semantics/altIdentifier/doi/http://dx.doi.org/10.1016/j.parkreldis.2015.09.025
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