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dc.contributor.author
Gagliardi, Juan A.
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Maciel, Neiva
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Castellano, José L.
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Masoli, Osvaldo
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Miksztowicz, Verónica Julieta
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Berg, Gabriela Alicia
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Bermejo, Emilse
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Lazzari, María Ángela
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Gelpi, Ricardo Jorge
dc.date.available
2018-03-15T17:07:25Z
dc.date.issued
2016-01
dc.identifier.citation
Gagliardi, Juan A.; Maciel, Neiva; Castellano, José L.; Masoli, Osvaldo; Miksztowicz, Verónica Julieta; et al.; Relationship between endothelial progenitor cells and vascular endothelial growth factor and its variation with exercise; Pergamon-Elsevier Science Ltd; Thrombosis Research; 137; 1-2016; 92-96
dc.identifier.issn
0049-3848
dc.identifier.uri
http://hdl.handle.net/11336/38917
dc.description.abstract
Background: The aim of our study was to evaluate the effect of programmed physical activity and a single exercise test on the number of CD309+ circulating endothelial progenitor cell (EPC) and their relation to the variation in plasma levels of VEGF in chronic coronary patients. Methods: 21 patients < 75 years with chronic stable coronary artery disease were included. All patients underwent exercise myocardial perfusion SPECT. Then, participants were divided into two groups: one group (11 patients) underwent cardiac rehabilitation program and the other (10 patients) continued with the standard treatment. Blood samples were obtained at baseline, 30 min after exercise ended and at one and three months during follow-up. Results: VEGF values decreased significantly after exercise SPECT test. After one month, there was a significant increase in VEGF levels compared to those measured immediately after exercise. All patients showed a decrease in the values of EPC at 1 and 3-month follow-up. There was an inverse and statistically significant relation between change of EPC and VEGF between the baseline and 1 month. Conclusions: The increase of VEGF at 1-month, with respect to baseline values correlated with decreased levels of EPC. This association was independent of the onset of ischemia in the perfusion study.
dc.format
application/pdf
dc.language.iso
eng
dc.publisher
Pergamon-Elsevier Science Ltd
dc.rights
info:eu-repo/semantics/openAccess
dc.rights.uri
https://creativecommons.org/licenses/by-nc-nd/2.5/ar/
dc.subject
Vegf
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Excercise
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Progenitor Cell
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Otras Ciencias de la Salud
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Ciencias de la Salud
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CIENCIAS MÉDICAS Y DE LA SALUD
dc.title
Relationship between endothelial progenitor cells and vascular endothelial growth factor and its variation with exercise
dc.type
info:eu-repo/semantics/article
dc.type
info:ar-repo/semantics/artículo
dc.type
info:eu-repo/semantics/publishedVersion
dc.date.updated
2018-03-14T17:13:50Z
dc.journal.volume
137
dc.journal.pagination
92-96
dc.journal.pais
Estados Unidos
dc.description.fil
Fil: Gagliardi, Juan A.. Gobierno de la Ciudad de Buenos Aires. Ministerio de Salud; Argentina
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Fil: Maciel, Neiva. Ciudad Autónoma de Buenos Aires. Hospital General de Agudos "Dr. Cosme Argerich"; Argentina
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Fil: Castellano, José L.. Ciudad Autónoma de Buenos Aires. Hospital General de Agudos "Dr. Cosme Argerich"; Argentina
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Fil: Masoli, Osvaldo. Ciudad Autónoma de Buenos Aires. Hospital General de Agudos "Dr. Cosme Argerich"; Argentina
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Fil: Miksztowicz, Verónica Julieta. Universidad de Buenos Aires. Facultad de Farmacia y Bioquímica. Departamento de Bioquímica Clínica; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina
dc.description.fil
Fil: Berg, Gabriela Alicia. Universidad de Buenos Aires. Facultad de Farmacia y Bioquímica. Departamento de Bioquímica Clínica; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina
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Fil: Bermejo, Emilse. Academia Nacional de Medicina de Buenos Aires. Instituto de Investigaciones Hematológicas "Mariano R. Castex"; Argentina
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Fil: Lazzari, María Ángela. Academia Nacional de Medicina de Buenos Aires. Instituto de Investigaciones Hematológicas "Mariano R. Castex"; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina
dc.description.fil
Fil: Gelpi, Ricardo Jorge. Universidad de Buenos Aires. Facultad de Medicina. Instituto de Fisiopatología Cardiovascular; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina
dc.journal.title
Thrombosis Research
dc.relation.alternativeid
info:eu-repo/semantics/altIdentifier/doi/http://dx.doi.org/10.1016/j.thromres.2015.11.012
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info:eu-repo/semantics/altIdentifier/url/https://www.sciencedirect.com/science/article/pii/S0049384815301882
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