Mostrar el registro sencillo del ítem
dc.contributor.author
Rinaldi, Ana Laura
dc.contributor.author
Carballo, Romina Raquel
dc.date.available
2018-03-14T18:57:27Z
dc.date.issued
2016-06
dc.identifier.citation
Rinaldi, Ana Laura; Carballo, Romina Raquel; Impedimetric non-enzymatic glucose sensor based on nickel hydroxide thin film onto gold electrode; Elsevier Science Sa; Sensors and Actuators B: Chemical; 228; 6-2016; 43-52
dc.identifier.issn
0925-4005
dc.identifier.uri
http://hdl.handle.net/11336/38763
dc.description.abstract
A non-enzymatic glucose sensor based on a thin layer of nickel immobilized on a gold electrode (EAuNi(OH)2) was used to perform impedimetric determination of glucose. The electrodeposition solution, composed of 0.010 M Ni(NO3)2·6H2O and 1 M of chloride, allows only one active catalyst (NiOOH) to be present on the gold electrode surface after activation with 0.1 M KOH. Electrochemical oxidation of glucose on EAuNi(OH)2 electrode was evaluated by Cyclic Voltammetry (CV) and Electrochemical Impedance Spectroscopy (EIS) in the concentration range of 0-14.8 mM of analyte. Ip/v1/2 vs scan rate graph shows a typical catalytic behavior by EAuNi(OH)2 toward glucose oxidation. Measurements in the presence of possible interfering species (ascorbic acid, uric acid, dopamine) did not affect the response of the analyte of interest. EIS offers good sensibility and selectivity for the glucose detection by non-enzymatic glucose sensor as an alternative to conventional methods. A single-frequency impedance method is proposed as transduction principle. For that, the parameters of complex impedance (module, phase, real and imaginary impedance) at each frequency were evaluated in function of glucose concentration and in terms of correlation coefficient. These analyses show a better linear response for the module of impedance (|Z|) in the range of 0-2 mM of glucose at 0.1 Hz (R2 = 0.984) with a slope of 484.7 Ω mM-1 of glucose. Finally, EAuNi(OH)2 was successfully applied to the assay of glucose in blood samples.
dc.format
application/pdf
dc.language.iso
eng
dc.publisher
Elsevier Science Sa
dc.rights
info:eu-repo/semantics/openAccess
dc.rights.uri
https://creativecommons.org/licenses/by-nc-nd/2.5/ar/
dc.subject
Blood Sample
dc.subject
Electrochemical Impedance Spectroscopy
dc.subject
Glucose
dc.subject
Nickel Gold Electrode
dc.subject
Non-Enzymatic Sensor
dc.subject.classification
Otras Ciencias Químicas
dc.subject.classification
Ciencias Químicas
dc.subject.classification
CIENCIAS NATURALES Y EXACTAS
dc.title
Impedimetric non-enzymatic glucose sensor based on nickel hydroxide thin film onto gold electrode
dc.type
info:eu-repo/semantics/article
dc.type
info:ar-repo/semantics/artículo
dc.type
info:eu-repo/semantics/publishedVersion
dc.date.updated
2018-03-14T17:07:02Z
dc.journal.volume
228
dc.journal.pagination
43-52
dc.journal.pais
Países Bajos
dc.journal.ciudad
Amsterdam
dc.description.fil
Fil: Rinaldi, Ana Laura. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Houssay. Instituto de Química y Físico-Química Biológicas ; Argentina
dc.description.fil
Fil: Carballo, Romina Raquel. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Houssay. Instituto de Química y Físico-Química Biológicas ; Argentina
dc.journal.title
Sensors and Actuators B: Chemical
dc.relation.alternativeid
info:eu-repo/semantics/altIdentifier/doi/http://dx.doi.org/10.1016/j.snb.2015.12.101
dc.relation.alternativeid
info:eu-repo/semantics/altIdentifier/url/https://www.sciencedirect.com/science/article/pii/S092540051530825X
Archivos asociados