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dc.contributor.author
Magalhães Barros, Mário Henrique
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Leite, Edinalva
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Chabay, Paola Andrea
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Morais, Vera
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Stefanoff, Gustavo
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Hassan, Rocio
dc.date.available
2018-03-12T20:25:28Z
dc.date.issued
2015-02
dc.identifier.citation
Magalhães Barros, Mário Henrique; Leite, Edinalva; Chabay, Paola Andrea; Morais, Vera; Stefanoff, Gustavo; et al.; Diagnosing lymphoma in a setting with a high burden of infection: a pediatric case of Epstein-Barr virus-associated aggressive B-cell lymphoma with t(8;14) (q23;q32) and extensive necrosis mimicking tuberculosis; Sociedade Brasileira de Medicina Tropical; Revista da Sociedade Brasileira de Medicina Tropical; 48; 1; 2-2015; 108-111
dc.identifier.issn
0037-8682
dc.identifier.uri
http://hdl.handle.net/11336/38582
dc.description.abstract
The association of lymphoma with necrotic granuloma can pose diagnostic challenges and delay treatment, especially in settings with a high burden of infection. In these settings, the timely use of cytogenetic and molecular methods is most relevant. Here, we report a case of B-cell lymphoma with t (8;14) in a 5-year-old male child. The lymphoma was associated with necrotic granuloma and was initially misdiagnosed as tuberculosis. Polymerase chain reaction was used to detect clonal lymphoproliferation and to rule out Mycobacterium tuberculosis infection. Tumor cells harbored Epstein-Barr virus and expressed CD20, CD10, BCL6, and Ki67 (30%), leading to the diagnosis of B-cell lymphoma with features intermediate between diffuse large B-cell lymphoma and Burkitt lymphoma.
dc.format
application/pdf
dc.language.iso
eng
dc.publisher
Sociedade Brasileira de Medicina Tropical
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dc.rights
info:eu-repo/semantics/openAccess
dc.rights.uri
https://creativecommons.org/licenses/by-nc/2.5/ar/
dc.subject
Epstein-Barr Virus
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Burkitt
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Tuberculosis
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Traslocation
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Non-Hodgkin Lymphoma
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Necrotic Granuloma
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Medicina Critica y de Emergencia
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Medicina Clínica
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CIENCIAS MÉDICAS Y DE LA SALUD
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dc.title
Diagnosing lymphoma in a setting with a high burden of infection: a pediatric case of Epstein-Barr virus-associated aggressive B-cell lymphoma with t(8;14) (q23;q32) and extensive necrosis mimicking tuberculosis
dc.type
info:eu-repo/semantics/article
dc.type
info:ar-repo/semantics/artículo
dc.type
info:eu-repo/semantics/publishedVersion
dc.date.updated
2018-03-08T19:02:51Z
dc.identifier.eissn
1678-9849
dc.journal.volume
48
dc.journal.number
1
dc.journal.pagination
108-111
dc.journal.pais
Brasil
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dc.journal.ciudad
Uberaba
dc.description.fil
Fil: Magalhães Barros, Mário Henrique. Instituto Nacional de Câncer; Brasil
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Fil: Leite, Edinalva. Universidade Federal de Pernambuco; Brasil
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Fil: Chabay, Paola Andrea. Gobierno de la Ciudad de Buenos Aires. Hospital General de Niños ; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina
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Fil: Morais, Vera. Universidade Federal de Pernambuco; Brasil
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Fil: Stefanoff, Gustavo. Instituto Nacional de Câncer; Brasil
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Fil: Hassan, Rocio. Instituto Nacional de Câncer; Brasil
dc.journal.title
Revista da Sociedade Brasileira de Medicina Tropical
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dc.relation.alternativeid
info:eu-repo/semantics/altIdentifier/doi/http://dx.doi.org/10.1590/0037-8682-0153-2014
dc.relation.alternativeid
info:eu-repo/semantics/altIdentifier/url/http://ref.scielo.org/pfrny8
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