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dc.contributor.author
Carrascosa, Patricia M.  
dc.contributor.author
Deviggiano, Alejandro  
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Capunay, Carlos  
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Campisi, Roxana  
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López de Munain, Marina  
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Vallejos, Javier  
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Tajer, Carlos  
dc.contributor.author
Rodriguez Granillo, Gaston Alfredo  
dc.date.available
2018-03-12T15:43:37Z  
dc.date.issued
2015-04  
dc.identifier.citation
Carrascosa, Patricia M.; Deviggiano, Alejandro; Capunay, Carlos; Campisi, Roxana; López de Munain, Marina; et al.; Incremental value of myocardial perfusion over coronary angiography by spectral computed tomography in patients with intermediate to high likelihood of coronary artery disease; Elsevier Ireland; European Journal Of Radiology; 84; 4; 4-2015; 637-642  
dc.identifier.issn
0720-048X  
dc.identifier.uri
http://hdl.handle.net/11336/38521  
dc.description.abstract
Purpose: We sought to explore the diagnostic performance of dual energy computed tomography (DECT) for the evaluation of myocardial perfusion in patients with intermediate to high likelihood of coronary artery disease (CAD). Materials and methods: Consecutive patients with known or suspected CAD referred for myocardial perfusion imaging by single-photon emission computed tomography (SPECT) constituted the study population and were scanned using a DECT scanner equipped with gemstone detectors for spectral imaging, and a SPECT. The same pharmacological stress was used for both scans. Results: Twenty-five patients were prospectively included in the study protocol. The mean age was 63.4 ± 10.6 years. The total mean effective radiation dose was 7.5 ± 1.2 mSv with DECT and 8.2 ± 1.7 mSv with SPECT (p = 0.007). A total of 425 left ventricular segments were evaluated by DECT, showing a reliable accuracy for the detection of reversible perfusion defects [area under ROC curve (AUC) 0.84 (0.80-0.87)]. Furthermore, adding stress myocardial perfusion provided a significant incremental value over anatomical evaluation alone by computed tomography coronary angiography [AUC 0.70 (0.65-0.74), p = 0.003]. Conclusions: In this pilot investigation, stress myocardial perfusion by DECT demonstrated a significant incremental value over anatomical evaluation alone by CTCA for the detection of reversible perfusion defects.  
dc.format
application/pdf  
dc.language.iso
eng  
dc.publisher
Elsevier Ireland  
dc.rights
info:eu-repo/semantics/openAccess  
dc.rights.uri
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/  
dc.subject
Dipyridamole  
dc.subject
Imaging  
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Ischemia  
dc.subject
Spect  
dc.subject.classification
Medicina Critica y de Emergencia  
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Medicina Clínica  
dc.subject.classification
CIENCIAS MÉDICAS Y DE LA SALUD  
dc.title
Incremental value of myocardial perfusion over coronary angiography by spectral computed tomography in patients with intermediate to high likelihood of coronary artery disease  
dc.type
info:eu-repo/semantics/article  
dc.type
info:ar-repo/semantics/artículo  
dc.type
info:eu-repo/semantics/publishedVersion  
dc.date.updated
2018-03-09T14:44:28Z  
dc.journal.volume
84  
dc.journal.number
4  
dc.journal.pagination
637-642  
dc.journal.pais
Irlanda  
dc.journal.ciudad
Shannon  
dc.description.fil
Fil: Carrascosa, Patricia M.. Diagnóstico Maipú; Argentina  
dc.description.fil
Fil: Deviggiano, Alejandro. Diagnóstico Maipú; Argentina  
dc.description.fil
Fil: Capunay, Carlos. Diagnóstico Maipú; Argentina  
dc.description.fil
Fil: Campisi, Roxana. Diagnóstico Maipú; Argentina  
dc.description.fil
Fil: López de Munain, Marina. Diagnóstico Maipú; Argentina  
dc.description.fil
Fil: Vallejos, Javier. Diagnóstico Maipú; Argentina  
dc.description.fil
Fil: Tajer, Carlos. Diagnóstico Maipú; Argentina  
dc.description.fil
Fil: Rodriguez Granillo, Gaston Alfredo. Diagnóstico Maipú; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina  
dc.journal.title
European Journal Of Radiology  
dc.relation.alternativeid
info:eu-repo/semantics/altIdentifier/doi/http://dx.doi.org/10.1016/j.ejrad.2014.12.013  
dc.relation.alternativeid
info:eu-repo/semantics/altIdentifier/url/https://www.sciencedirect.com/science/article/pii/S0720048X15000029