Artículo
Reducing risks in type 1 diabetes using H∞ Control
Colmegna, Patricio Hernán
; Sanchez Peña, Ricardo Salvador
; Gondhalekar, Ravi; Dassau, Eyal; Doyle, Francis J.
![Icon](/themes/CONICETDigital/images/conicet.png)
![Icon](/themes/CONICETDigital/images/conicet.png)
Fecha de publicación:
12/2014
Editorial:
Institute of Electrical and Electronics Engineers
Revista:
Ieee Transactions On Bio-medical Engineering
ISSN:
0018-9294
Idioma:
Inglés
Tipo de recurso:
Artículo publicado
Clasificación temática:
Resumen
A control scheme was designed in order to reduce the risks of hyperglycemia and hypoglycemia in type 1 diabetes mellitus (T1DM). This structure is composed of three main components: an H∞ robust controller, an insulin feedback loop (IFL), and a safety mechanism (SM). A control-relevant model that is employed to design the robust controller is identified. The identification procedure is based on the distribution version of the UVA/Padova metabolic simulator using the simulation adult cohort. The SM prevents dangerous scenarios by acting upon a prediction of future glucose levels, and the IFL modifies the loop gain in order to reduce postprandial hypoglycemia risks. The procedure is tested on the complete in silico adult cohort of the UVA/Padova metabolic simulator, which has been accepted by the Food and Drug Administration (FDA) in lieu of animal trials.
Palabras clave:
Hyperglycemia
,
Hypoglycemia
,
H&Infin; Control
,
Type 1 Diabetes
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Articulos(SEDE CENTRAL)
Articulos de SEDE CENTRAL
Articulos de SEDE CENTRAL
Citación
Colmegna, Patricio Hernán; Sanchez Peña, Ricardo Salvador; Gondhalekar, Ravi; Dassau, Eyal; Doyle, Francis J.; Reducing risks in type 1 diabetes using H∞ Control; Institute of Electrical and Electronics Engineers; Ieee Transactions On Bio-medical Engineering; 61; 12; 12-2014; 2939-2947
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