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dc.contributor.author Lasserre, Andrea
dc.contributor.author Gonzalez Echeverria, Fernanda
dc.contributor.author Moules, Carolina
dc.contributor.author Tezon, Jorge Guillermo
dc.contributor.author Miranda, Patricia Vivian
dc.contributor.author Vazquez, Monica Hebe
dc.date.available 2018-02-11T22:33:41Z
dc.date.issued 2003-06
dc.identifier.citation Lasserre, Andrea; Gonzalez Echeverria, Fernanda; Moules, Carolina; Tezon, Jorge Guillermo; Miranda, Patricia Vivian; et al.; Identification of human sperm proteins involved in the interaction with homologous zona pellucida; American Society for Reproductive Medicine; Fertility and Sterility; 79; 3; 6-2003; 1606-1615
dc.identifier.issn 0015-0282
dc.identifier.uri http://hdl.handle.net/11336/36411
dc.description.abstract To identify human sperm proteins involved in homologous zona pellucida (ZP) interaction.Fertilization results from successful interaction between the female and male gametes. Capacitated human spermatozoa initially bind, in a species-specific manner, with the zona pellucida (ZP), an extracellular coat that surrounds all mammalian eggs. As a result of this interaction, spermatozoa undergo an exocytotic process called the acrosome reaction, which allows sperm penetration through the ZP and fusion with the oocyte plasma membrane (1, 2). In many mammals, including humans, it has been shown that the ZP is composed of three glycoproteins, called ZP1, ZP2, and ZP3, which are well characterized at biochemical and molecular level (3, 4). Of the three components, ZP3 is responsible for primary sperm binding to the ZP and induction of the acrosome reaction (AR) (5, 6), while ZP2 would participate in secondary binding to the ZP (7).
dc.format application/pdf
dc.language.iso eng
dc.publisher American Society for Reproductive Medicine
dc.rights info:eu-repo/semantics/restrictedAccess
dc.rights.uri https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
dc.subject SPERM
dc.subject ZONA PELLUCIDA
dc.subject FERTILIZATION
dc.subject ANTIBODIES
dc.subject EPIDIDYMIS
dc.subject SPERM-EGG INTERACTION
dc.subject.classification Biología Reproductiva
dc.subject.classification Ciencias Biológicas
dc.subject.classification CIENCIAS NATURALES Y EXACTAS
dc.subject.classification Bioquímica y Biología Molecular
dc.subject.classification Medicina Básica
dc.subject.classification CIENCIAS MÉDICAS Y DE LA SALUD
dc.title Identification of human sperm proteins involved in the interaction with homologous zona pellucida
dc.type info:eu-repo/semantics/article
dc.type info:ar-repo/semantics/artículo
dc.type info:eu-repo/semantics/publishedVersion
dc.date.updated 2017-12-28T17:49:41Z
dc.journal.volume 79
dc.journal.number 3
dc.journal.pagination 1606-1615
dc.journal.pais Estados Unidos
dc.description.fil Fil: Lasserre, Andrea. Consejo Nacional de Investigaciones Científicas y Técnicas. Instituto de Biología y Medicina Experimental. Fundación de Instituto de Biología y Medicina Experimental. Instituto de Biología y Medicina Experimental; Argentina
dc.description.fil Fil: Gonzalez Echeverria, Fernanda. Fertilab; Argentina
dc.description.fil Fil: Moules, Carolina. Consejo Nacional de Investigaciones Científicas y Técnicas. Instituto de Biología y Medicina Experimental. Fundación de Instituto de Biología y Medicina Experimental. Instituto de Biología y Medicina Experimental; Argentina
dc.description.fil Fil: Tezon, Jorge Guillermo. Consejo Nacional de Investigaciones Científicas y Técnicas. Instituto de Biología y Medicina Experimental. Fundación de Instituto de Biología y Medicina Experimental. Instituto de Biología y Medicina Experimental; Argentina
dc.description.fil Fil: Miranda, Patricia Vivian. Consejo Nacional de Investigaciones Científicas y Técnicas. Instituto de Biología y Medicina Experimental. Fundación de Instituto de Biología y Medicina Experimental. Instituto de Biología y Medicina Experimental; Argentina
dc.description.fil Fil: Vazquez, Monica Hebe. Consejo Nacional de Investigaciones Científicas y Técnicas. Instituto de Biología y Medicina Experimental. Fundación de Instituto de Biología y Medicina Experimental. Instituto de Biología y Medicina Experimental; Argentina
dc.journal.title Fertility and Sterility
dc.relation.alternativeid info:eu-repo/semantics/altIdentifier/url/http://www.fertstert.org/article/S0015-0282(03)00251-6/abstract
dc.relation.alternativeid info:eu-repo/semantics/altIdentifier/doi/http://dx.doi.org/10.1016/S0015-0282(03)00251-6
dc.relation.alternativeid info:eu-repo/semantics/altIdentifier/pmid/12801567
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info:eu-repo/semantics/restrictedAccess Excepto donde se diga explícitamente, este item se publica bajo la siguiente descripción: Creative Commons Attribution-NonCommercial-ShareAlike 2.5 Unported (CC BY-NC-SA 2.5)