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dc.contributor.author
Busso, D.
dc.contributor.author
Cohen, Debora Juana
dc.contributor.author
Da Ros, Vanina Gabriela
dc.contributor.author
Fissore, R.
dc.contributor.author
Cuasnicu, Patricia Sara
dc.date.available
2018-02-09T01:36:03Z
dc.date.issued
2003-05
dc.identifier.citation
Busso, D.; Cohen, Debora Juana; Da Ros, Vanina Gabriela; Fissore, R.; Cuasnicu, Patricia Sara; Studies on the participation of epididymal sperm protein DE/CRISP-1 in egg activation; C. M. B. Association; Cellular and Molecular Biology; 49; 3; 5-2003; 407-412
dc.identifier.issn
0145-5680
dc.identifier.uri
http://hdl.handle.net/11336/36271
dc.description.abstract
Protein DE (32 kDa) associates with sperm during epididymal maturation and participates in sperm-egg fusion through its binding to complementary sites on the egg surface. In the present work we investigated the participation of DE in two mechanisms probably involved in egg activation: the ability of DE to trigger activation by its interaction with the binding sites on the egg surface (receptor model) and its ability to regulate intracellular calcium channels (sperm factor model). The incubation of eggs with DE did not promote activation parameters such as calcium oscillations or meiosis resumption. Secondly, microinjection of DE into eggs was ineffective in either eliciting calcium release or modifying oscillations induced by an activating sperm extract. Together, these results argue against the participation of DE in egg activation, restricting the activity of this protein and its egg binding sites to the sperm-egg fusion process.
dc.format
application/pdf
dc.language.iso
eng
dc.publisher
C. M. B. Association
dc.rights
info:eu-repo/semantics/openAccess
dc.rights.uri
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
dc.subject
Fertilization
dc.subject
Oocytes
dc.subject
Epididymal Secretory Proteins
dc.subject
Sperm Capacitation
dc.subject
Spermatozoa
dc.subject.classification
Biología Reproductiva
dc.subject.classification
Ciencias Biológicas
dc.subject.classification
CIENCIAS NATURALES Y EXACTAS
dc.subject.classification
Bioquímica y Biología Molecular
dc.subject.classification
Medicina Básica
dc.subject.classification
CIENCIAS MÉDICAS Y DE LA SALUD
dc.title
Studies on the participation of epididymal sperm protein DE/CRISP-1 in egg activation
dc.type
info:eu-repo/semantics/article
dc.type
info:ar-repo/semantics/artículo
dc.type
info:eu-repo/semantics/publishedVersion
dc.date.updated
2017-12-28T13:41:59Z
dc.journal.volume
49
dc.journal.number
3
dc.journal.pagination
407-412
dc.journal.pais
Francia
dc.journal.ciudad
Paris
dc.description.fil
Fil: Busso, D.. Consejo Nacional de Investigaciones Científicas y Técnicas. Instituto de Biología y Medicina Experimental. Fundación de Instituto de Biología y Medicina Experimental. Instituto de Biología y Medicina Experimental; Argentina
dc.description.fil
Fil: Cohen, Debora Juana. Consejo Nacional de Investigaciones Científicas y Técnicas. Instituto de Biología y Medicina Experimental. Fundación de Instituto de Biología y Medicina Experimental. Instituto de Biología y Medicina Experimental; Argentina
dc.description.fil
Fil: Da Ros, Vanina Gabriela. Consejo Nacional de Investigaciones Científicas y Técnicas. Instituto de Biología y Medicina Experimental. Fundación de Instituto de Biología y Medicina Experimental. Instituto de Biología y Medicina Experimental; Argentina
dc.description.fil
Fil: Fissore, R.. University of Massachussets; Estados Unidos
dc.description.fil
Fil: Cuasnicu, Patricia Sara. Consejo Nacional de Investigaciones Científicas y Técnicas. Instituto de Biología y Medicina Experimental. Fundación de Instituto de Biología y Medicina Experimental. Instituto de Biología y Medicina Experimental; Argentina
dc.journal.title
Cellular and Molecular Biology
dc.relation.alternativeid
info:eu-repo/semantics/altIdentifier/pmid/12887093


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  • Articulos(IBYME) [1151]
    Articulos de INST.DE BIOLOGIA Y MEDICINA EXPERIMENTAL (I)

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