Mostrar el registro sencillo del ítem
dc.contributor.author
Aldana, Ana Agustina
dc.contributor.author
Rial Hermida, María Isabel
dc.contributor.author
Abraham, Gustavo Abel
dc.contributor.author
Concheiro, Angel
dc.contributor.author
Alvarez Lorenzo, Carmen
dc.date.available
2018-01-24T21:27:06Z
dc.date.issued
2017-09-18
dc.identifier.citation
Aldana, Ana Agustina; Rial Hermida, María Isabel; Abraham, Gustavo Abel; Concheiro, Angel; Alvarez Lorenzo, Carmen; Temperature-sensitive biocompatible IPN hydrogels based on poly(NIPA-PEGdma) and photocrosslinkable gelatin methacrylate; Taylor & Francis; Soft Materials; 15; 4; 18-9-2017; 341-349
dc.identifier.issn
1539-445X
dc.identifier.uri
http://hdl.handle.net/11336/34536
dc.description.abstract
The future of tissue engineering and regenerative medicine relies on the development of biomimetic extracellular matrices (ECM). Hydrogels based on biological and synthetic macromolecules could mimic native ECM which is an interpenetrating network (IPN) of proteins and other biomacromolecules. In thisstudy, gelatin and N-isopropylacrylamide-based IPN hydrogels, named as NPxG, were developed to fabricate 3D matrix systems. A series of IPN hydrogels with different contents in poly(NIPA-PEGdma) (NPx) and gelatin methacrylate (GelMA) were synthesized. NPx and GelMA were characterized by Habeeb?s assay, FTIR and 1H-NMR. IPN hydrogels were fully characterized by ATR-FTIR, swellingmeasurements, optical microscopy, SEM, DSC and rheology. Optical microscopy images and rheology demonstrated that hydrogel properties change around 37ºC. Above LCST, the translucent colorless hydrogel shifted to opaque white hydrogel and the storage modulus increased. A wide range of IPN gels with different swelling properties and potential applications in different fields can be produced by controlling experimental parameters.
dc.format
application/pdf
dc.language.iso
eng
dc.publisher
Taylor & Francis
dc.rights
info:eu-repo/semantics/openAccess
dc.rights.uri
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
dc.subject
Termoresponsive Polymers
dc.subject
Gelatin
dc.subject
Hydrogels
dc.subject
Networks
dc.subject
Interpenetrating Network
dc.subject
Thermosensitive Hydrogels
dc.subject
Cell Culture
dc.subject.classification
Biotecnología Industrial
dc.subject.classification
Biotecnología Industrial
dc.subject.classification
INGENIERÍAS Y TECNOLOGÍAS
dc.title
Temperature-sensitive biocompatible IPN hydrogels based on poly(NIPA-PEGdma) and photocrosslinkable gelatin methacrylate
dc.type
info:eu-repo/semantics/article
dc.type
info:ar-repo/semantics/artículo
dc.type
info:eu-repo/semantics/publishedVersion
dc.date.updated
2018-01-18T14:16:20Z
dc.journal.volume
15
dc.journal.number
4
dc.journal.pagination
341-349
dc.journal.pais
Estados Unidos
dc.journal.ciudad
Nueva York
dc.description.fil
Fil: Aldana, Ana Agustina. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Mar del Plata. Instituto de Investigaciones en Ciencia y Tecnología de Materiales. Universidad Nacional de Mar del Plata. Facultad de Ingeniería. Instituto de Investigaciones en Ciencia y Tecnología de Materiales; Argentina
dc.description.fil
Fil: Rial Hermida, María Isabel. Universidad de Santiago de Compostela; España
dc.description.fil
Fil: Abraham, Gustavo Abel. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Mar del Plata. Instituto de Investigaciones en Ciencia y Tecnología de Materiales. Universidad Nacional de Mar del Plata. Facultad de Ingeniería. Instituto de Investigaciones en Ciencia y Tecnología de Materiales; Argentina
dc.description.fil
Fil: Concheiro, Angel. Universidad de Santiago de Compostela; España
dc.description.fil
Fil: Alvarez Lorenzo, Carmen. Universidad de Santiago de Compostela; España
dc.journal.title
Soft Materials
dc.relation.alternativeid
info:eu-repo/semantics/altIdentifier/url/https://www.tandfonline.com/doi/full/10.1080/1539445X.2017.1378677
dc.relation.alternativeid
info:eu-repo/semantics/altIdentifier/doi/http://dx.doi.org/10.1080/1539445X.2017.1378677
Archivos asociados