Artículo
Reciprocal interactions between tumor and endothelial cells: Effects of selective vasopressin V2 receptor peptide agonists
Fecha de publicación:
01/2014
Editorial:
Smart Science & Technology
Revista:
Cancer Cell & Microenvironment
ISSN:
2331-091X
Idioma:
Inglés
Tipo de recurso:
Artículo publicado
Clasificación temática:
Resumen
Recent experimental evidence suggested that the synthetic peptide desmopressin (DDAVP) interferes tumor angiogenesis by inducing the formation of angiostatin. It is also known that DDAVP stimulates the endothelial release of von Willebrand factor, a key element in resistance to metastasis. Vasopressin V2 receptor agonists such as DDAVP seem to evoke dual angiostatic and antimetastatic effects, breaking cooperative interactions of tumor and endothelial cells during tumor progression.
Palabras clave:
Tumor Microenvironment
,
Angiogenesis
,
Metastasis
,
Vasopressin
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Tamaño:
453.2Kb
Formato:
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Licencia
Excepto donde se diga explícitamente, este item se publica bajo la siguiente descripción:
Creative Commons Attribution 2.5 Unported (CC BY 2.5)
Identificadores
Colecciones
Articulos(SEDE CENTRAL)
Articulos de SEDE CENTRAL
Articulos de SEDE CENTRAL
Citación
Garona, Juan; Alonso, Daniel Fernando; Reciprocal interactions between tumor and endothelial cells: Effects of selective vasopressin V2 receptor peptide agonists; Smart Science & Technology; Cancer Cell & Microenvironment; 1; 1-2014; 1-5
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